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Last Updated: January 1, 2026

Claims for Patent: 10,836,814


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Summary for Patent: 10,836,814
Title:Anti-semaphorin 3A antibody and treatment of Alzheimer's disease and inflammatory immune diseases using same
Abstract:The present invention mainly addresses the problem of providing an antibody against semaphorin 3A protein, said antibody enabling effective prevention and/or treatment of a disease, in which Sema 3A protein participates, such as a neurodegenerative disease, autoimmune disease, inflammatory disease, cancer, infectious disease, etc. or disseminated intravascular coagulation syndrome. An anti-Sema 3A antibody comprising CDRs having specific amino acid sequences (SEQ ID NOS: 1-6, 60-62, 64-66, 68-70, 72-74, 76-78, 80-82, 84-86 and 88-90) enables effective prevention and/or treatment of a disease, in which Sema 3A protein participates, such as a neurodegenerative disease, autoimmune disease, inflammatory disease, cancer, infectious disease, etc. or disseminated intravascular coagulation syndrome and, therefore, remarkably ameliorates symptoms associated with such a disease.
Inventor(s):Yoshio Goshima, Fumio Nakamura, Naoya Yamashita, Hidetaka Seo, Shuichi Hashimoto, Koji Murakami, Naoki Takahashi, Yukie Sasakura
Assignee: Yokohama City University , Chiome Bioscience Inc
Application Number:US15/847,740

Details for Patent 10,836,814

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Csl Behring Lengnau Ag AFSTYLA antihemophilic factor (recombinant), single chain For Injection 125591 May 25, 2016 10,836,814 2037-12-19
Csl Behring Lengnau Ag AFSTYLA antihemophilic factor (recombinant), single chain For Injection 125591 March 31, 2017 10,836,814 2037-12-19
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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