Last Updated: August 4, 2026

Claims for Patent: 10,682,395

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Summary for Patent: 10,682,395

Title:	Dry growth hormone composition transiently linked to a polymer carrier
Abstract:	The present invention relates to dry compositions of rhGH polymer prodrug containing a lyoprotectant and, optionally, one or more than one excipient. Such compositions are stable for at least 1 year, when stored at 2-8° C. The invention further relates to methods of manufacturing said compositions, containers comprising such composition as well as a kit of parts.
Inventor(s):	Rasmussen Grethe Nørskov, Kindermann Susanne, Rau Harald, Wegge Thomas
Assignee:	Ascendis Pharma Endocrinology Division A/S
Application Number:	US15901350
Patent Claims:

Details for Patent 10,682,395

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Ascendis Pharma Endocrinology Division A/s	SKYTROFA	lonapegsomatropin-tcgd	For Injection	761177	August 25, 2021	⤷ Start Trial	2038-02-21
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,682,395

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Country	Patent Number	Estimated Expiration
South Africa	201204334	⤷ Start Trial
World Intellectual Property Organization (WIPO)	2011073234	⤷ Start Trial
United States of America	9919033	⤷ Start Trial
United States of America	9511122	⤷ Start Trial
United States of America	2020261544	⤷ Start Trial
United States of America	2018185452	⤷ Start Trial
United States of America	2017056477	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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