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Last Updated: December 17, 2025

Claims for Patent: 10,676,536

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Summary for Patent: 10,676,536

Title:	Anti-coagulation factor XI antibodies
Abstract:	Antibodies that bind the apple 3 domain of human coagulation Factor XI and inhibit activation of FXI by coagulation factor XIIa as well as activation of FIX by FXIa are described.
Inventor(s):	Zhu Chen, Kenneth Ellsworth, James Milligan, Elizabeth Oldham, Dietmar Seiffert, Bianka Prinz
Assignee:	Merck Sharp and Dohme LLC , Adimab LLC
Application Number:	US15/619,620

Details for Patent 10,676,536

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Genentech, Inc.	TECENTRIQ	atezolizumab	Injection	761034	May 18, 2016	⤷ Get Started Free	2037-06-12
Genentech, Inc.	TECENTRIQ	atezolizumab	Injection	761034	March 08, 2019	⤷ Get Started Free	2037-06-12
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,676,536

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2017218371	⤷ Get Started Free
United States of America	2023287141	⤷ Get Started Free
United States of America	2020317811	⤷ Get Started Free
United States of America	2020308302	⤷ Get Started Free
United States of America	2020270364	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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