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Last Updated: December 28, 2025

Claims for Patent: 10,632,185


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Summary for Patent: 10,632,185
Title:Chimeric west nile/zika viruses and methods of use
Abstract:Chimeric flaviviruses that include non-coding regions, non-structural proteins, a capsid (C) protein and a portion of a premembrane (prM) signal sequence from West Nile virus (WNV), and a portion of a prM signal sequence, a prM protein and an E protein from Zika virus (VIKV) are described. Also described are compositions and methods for eliciting an immune response in a subject, such as an immune response directed against ZIKV. Diagnostic assays that utilize chimeric West Nile/Zika viruses are further described.
Inventor(s):Claire Y. H. Kinney
Assignee: US Department of Health and Human Services
Application Number:US16/315,897

Details for Patent 10,632,185

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Glaxosmithkline Biologicals SHINGRIX zoster vaccine recombinant, adjuvanted Injection 125614 October 20, 2017 10,632,185 2037-07-06
Glaxosmithkline Biologicals SHINGRIX zoster vaccine recombinant, adjuvanted For Injection 125614 July 23, 2021 10,632,185 2037-07-06
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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