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Last Updated: March 12, 2026

Claims for Patent: 10,485,884


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Summary for Patent: 10,485,884
Title:RNA formulation for immunotherapy
Abstract:The present invention is in the field of immunotherapy, in particular tumor immunotherapy. The present invention provides pharmaceutical formulations for delivering RNA to antigen presenting cells such as dendrite cells (DCs) in the spleen after systemic administration. In particular, the formulations described herein enable to induce an immune response after systemic administration of antigen-coding RNA.
Inventor(s):Ugur Sahin, Heinrich Haas, Sebastian Kreiter, Mustafa Diken, Daniel Fritz, Martin Meng, Lena Mareen Kranz, Kerstin Reuter
Assignee: TRON Translationale Onkologie an der Universitaetsmedizin der Johannes Gutenberg Universitaet Mainz gGmbH , Biontech SE
Application Number:US14/388,192

Details for Patent 10,485,884

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Biontech Manufacturing Gmbh COMIRNATY covid-19 vaccine, mrna For Injection 125742 August 23, 2021 ⤷  Get Started Free 2033-03-25
Biontech Manufacturing Gmbh COMIRNATY covid-19 vaccine, mrna For Injection 125742 September 11, 2023 ⤷  Get Started Free 2033-03-25
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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