Claims for Patent: 10,471,140

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Summary for Patent: 10,471,140

Title:	Composition for enhancing induction of humoral immunity, and vaccine pharmaceutical composition
Abstract:	The present invention aims to provide a composition for promoting humoral immunity induction and a vaccine pharmaceutical composition that can be universally used for various antigens in inducing humoral immunity to antigens, contain a Th2 reaction promoter, and exerts a high humoral immunity inducing effect. The present invention relates to a vaccine pharmaceutical composition containing an antigen for humoral immunity induction and at least one Th2 reaction promoter.
Inventor(s):	Shishido; Takuya (Osaka, JP), Asari; Daisuke (Osaka, JP), Matsushita; Kyohei (Osaka, JP), Hori; Mitsuhiko (Osaka, JP)
Assignee:	NOTTO DENKO CORPORATION (Osaka, JP)
Application Number:	16/388,266
Patent Claims:	1. A pharmaceutical composition, comprising: an antigen; and a G protein-coupled receptor ligand that is at least one selected from an antagonist for a Gi-coupled GPCR and an antagonist for a Gq-coupled GPCR. 2. The pharmaceutical composition according to claim 1, configured to be administered to a body surface. 3. The pharmaceutical composition according to claim 1, configured to be administered by intradermal injection, subcutaneous injection, or intramuscular injection. 4. The pharmaceutical composition according to claim 1, wherein the antagonist is selected from the group consisting of an adrenergic receptor antagonist, a muscarinic receptor antagonist, a dopamine receptor antagonist, a histamine receptor antagonist, a serotonin receptor antagonist, a PAF receptor antagonist, a purine receptor antagonist, a vasopressin receptor antagonist, an opioid receptor antagonist, a leukotriene receptor antagonist, and an angiotensin receptor antagonist.

Details for Patent 10,471,140

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Jubilant Hollisterstier Llc	N/A	positive skin test control-histamine	Injection	103891	March 13, 1924	⤷ Start Trial	2039-04-18
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

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