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Last Updated: December 28, 2025

Claims for Patent: 10,336,814


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Summary for Patent: 10,336,814
Title:Method for obtaining thin fibril collagen by contacting native collagen with an antibody
Abstract:A collagen material having a form of thin fibrils generally free of fibril-bundling proteogylcan interactions, and a method for providing the thin fibril collagen material from native collagen fibers. The method uses proteoglycan antibodies to disassociate the proteoglycan interactions in bundled collagen fibrils to provide the constituent fibrils. The process can be used as a model for arthritis and the resulting fibrils can be used to form new extracellular matrix biomaterials and new tissues.
Inventor(s):Joseph Orgel, Olga Antipova
Assignee: Matrix Odyssey LLC
Application Number:US15/257,089

Details for Patent 10,336,814

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Takeda Pharmaceuticals U.s.a., Inc. VPRIV velaglucerase alfa For Injection 022575 February 26, 2010 10,336,814 2036-09-06
Genentech, Inc. ACTEMRA tocilizumab Injection 125276 January 08, 2010 10,336,814 2036-09-06
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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