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Last Updated: March 27, 2026

Claims for Patent: 10,301,361


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Summary for Patent: 10,301,361
Title:α-hemolysin variants with altered characteristics
Abstract:Described herein are variants of alpha-hemolysin having at least one mutation selected from T12R, T12K, N17R, N17K or combinations of T12 and N17 mutations. The variants in some embodiments may further comprise H144A. The α-hemolysin variants have a decreased time to thread.
Inventor(s):Michael Dorwart, Daniel Korenblum
Assignee: Roche Sequencing Solutions Inc
Application Number:US14/924,861

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