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Last Updated: April 19, 2026

Claims for Patent: 10,253,075

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Summary for Patent: 10,253,075

Title:	WT1 antigenic polypeptide, and anti-tumor agent containing said polypeptide
Abstract:	[Problem] To provide a polypeptide which enables stimulation of numerous T cells of different derivation, and to induce strong immunological response against numerous types of cancers.[Solution] Provided is a fused polypeptide that includes a helper epitope derived from the WT1 protein, and a killer epitope derived from the WT1 protein, wherein the polypeptide includes a total of 3 to 6 of the helper epitopes and the killer epitopes per molecule of the fused polypeptide.
Inventor(s):	Takashi Nishimura, Yuji Heike, Yuji TOGASHI
Assignee:	Hokkaido University NUC , Bioimmulance Co Ltd , Tella Inc
Application Number:	US15/121,525

Details for Patent 10,253,075

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Bioverativ Therapeutics, Inc.	ALPROLIX	coagulation factor ix (recombinant), fc fusion protein	For Injection	125444	March 28, 2014	⤷ Start Trial	2035-02-26
Bioverativ Therapeutics, Inc.	ALPROLIX	coagulation factor ix (recombinant), fc fusion protein	For Injection	125444	February 18, 2016	⤷ Start Trial	2035-02-26
Bioverativ Therapeutics, Inc.	ALPROLIX	coagulation factor ix (recombinant), fc fusion protein	For Injection	125444	July 14, 2016	⤷ Start Trial	2035-02-26
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,253,075

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Country	Patent Number	Estimated Expiration
China	106029699	⤷ Start Trial
European Patent Office	3112378	⤷ Start Trial
Japan	2016210800	⤷ Start Trial
Japan	6005305	⤷ Start Trial
Japan	WO2015129790	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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