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Last Updated: March 3, 2026

Claims for Patent: 10,227,392


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Summary for Patent: 10,227,392
Title:ALK7:ActRIIB heteromultimers and uses thereof
Abstract:In certain aspects, the disclosure provides soluble heteromeric polypeptide complexes comprising an extracellular domain of an ALK7 receptor and an extracellular domain of ActRIIB. In certain aspects, these ALK7:ActRIIB heteromultimers are can be used to improve metabolic parameters in a patient in need thereof. In certain aspects, these ALK7:ActRIIB heteromultimers are can be used to treat or prevent one or more kidney-associated disease or condition in a patient in need thereof.
Inventor(s):Ravindra Kumar, Asya Grinberg, Dianne Sako, Robert Scott Pearsall, Roselyne Castonguay, Gang Li, Yossi Dagon, John Knopf
Assignee: Acceleron Pharma Inc
Application Number:US15/092,577

International Patent Family for US Patent 10,227,392

Country Patent Number Estimated Expiration
World Intellectual Property Organization (WIPO) 2016164503 ⤷  Get Started Free
World Intellectual Property Organization (WIPO) 2016164501 ⤷  Get Started Free
World Intellectual Property Organization (WIPO) 2016164497 ⤷  Get Started Free
World Intellectual Property Organization (WIPO) 2016164089 ⤷  Get Started Free
United States of America 2025197469 ⤷  Get Started Free
>Country >Patent Number >Estimated Expiration

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