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Last Updated: December 29, 2025

Claims for Patent: 10,105,423

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Summary for Patent: 10,105,423

Title:	C1-INH compositions and methods for the prevention and treatment of disorders associated with C1 esterase inhibitor deficiency
Abstract:	Compositions and methods for the treatment and/or prevention of disorders associated with C1 esterase inhibitor deficiency are disclosed.
Inventor(s):	Stephen Ruddy, Mark Cornell Manning, Ryan Erik Holcomb
Assignee:	Viropharma Biologics LLC
Application Number:	US15/837,693

Details for Patent 10,105,423

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Takeda Pharmaceuticals U.s.a., Inc.	CINRYZE	c1 esterase inhibitor (human)	For Injection	125267	October 10, 2008	10,105,423	2037-12-11
Csl Behring Gmbh	HAEGARDA	c1 esterase inhibitor subcutaneous (human)	For Injection	125606	June 22, 2017	10,105,423	2037-12-11
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,105,423

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Country	Patent Number	Estimated Expiration
South Africa	201806793	⤷ Get Started Free
South Africa	201706929	⤷ Get Started Free
South Africa	201507604	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2014145519	⤷ Get Started Free
United States of America	9616111	⤷ Get Started Free
United States of America	2020261556	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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