Last Updated: August 4, 2026

Claims for Patent: 10,098,930

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Summary for Patent: 10,098,930

Title:	PEGylated Recombinant Human Growth Hormone Compounds
Abstract:	A chemically modified human Growth Hormone (rhGH) prepared by attaching a transient linker which comprises a polyethylene glycol. The chemically modified protein may have a much longer lasting rhGH activity than that of the unmodified rhGH, enabling reduced dose and scheduling opportunities and the modified rhGH may not cause lipoatrophy. Also includes methods of use for the treatment and/or prevention of diseases or disorders in which use of growth hormone is beneficial.
Inventor(s):	Rau Harald, Kindermann Susanne, Lebmann Torben, Norskov Rasmussen Grethe, Hersel Ulrich, Wegge Thomas, Sprogoe Kennett
Assignee:	Ascendis Pharma Endocrinology Division A/S
Application Number:	US15000242
Patent Claims:

Details for Patent 10,098,930

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Ascendis Pharma Endocrinology Division A/s	SKYTROFA	lonapegsomatropin-tcgd	For Injection	761177	August 25, 2021	10,098,930	2036-01-19
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,098,930

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Country	Patent Number	Estimated Expiration
World Intellectual Property Organization (WIPO)	2009133137	⤷ Start Trial
United States of America	10960053	⤷ Start Trial
United States of America	12274737	⤷ Start Trial
United States of America	2011112021	⤷ Start Trial
>Country	>Patent Number	>Estimated Expiration

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