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Last Updated: March 26, 2026

Claims for Patent: 10,065,998


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Summary for Patent: 10,065,998
Title:Proteins specific for pyoverdine and pyochelin
Abstract:The present disclosure provides hNGAL muteins that bind a pyoverdine family member or pyochelin and can be used in various application including pharmaceutical applications, for example, to inhibit or reduce growth of P. aeruginosa. The present disclosure also concerns methods of making one or more pyoverdine- or pyochelin-binding muteins described herein as well as compositions comprising one or more of such muteins. The present disclosure further relates to nucleic acid molecules encoding such muteins and to methods for generation of such muteins and nucleic acid molecules. In addition, the application discloses therapeutic and/or diagnostic uses of these muteins as well as compositions comprising one or more of such muteins.
Inventor(s):Carsten Corvey, Heike Stump, Jochen Kruip, Bernhard CALANDRA, Astrid Rey, Nathalie KARST, Michael Mourez, Laurent Fraisse, Christine Rothe, Andrea Allersdorfer, Alexander Wiedenmann, Marlon Hinner, Bradley Lunde, Kristian Jensen, Martin Hülsmeyer
Assignee: Pieris Pharmaceuticals GmbH
Application Number:US15/726,577

Details for Patent 10,065,998

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. ACTEMRA tocilizumab Injection 125472 October 21, 2013 ⤷  Start Trial 2037-10-06
Genentech, Inc. ACTEMRA tocilizumab Injection 125472 November 19, 2018 ⤷  Start Trial 2037-10-06
Rare Disease Therapeutics, Inc. (rdt) ANAVIP crotalidae immune f(ab')2 (equine) For Injection 125488 May 06, 2015 ⤷  Start Trial 2037-10-06
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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