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Last Updated: December 18, 2025

Claims for Patent: 10,030,043

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Summary for Patent: 10,030,043

Title:	Method for the synthesis of clofarabine
Abstract:	The present invention relates to a method for the high yield production of the anticancer nucleoside clofarabine, the method comprising the preparation of 2-chloroadenosine by enzymatic transglycosylation between 2-chloroadenine and nucleosides, benzoylation, isomerization, sulfonate ester formation, fluorination, and deprotection.
Inventor(s):	Alexander Zabudkin, Victor Matvienko, Iaroslav MATVIIENKO, Volodymyr SYPCHENKO
Assignee:	Synbias Pharma AG
Application Number:	US15/306,265

Details for Patent 10,030,043

Glossary

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Expiredate
Takeda Pharmaceuticals U.s.a., Inc.	VPRIV	velaglucerase alfa	For Injection	022575	February 26, 2010	10,030,043	2035-04-22
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Expiredate

International Patent Family for US Patent 10,030,043

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Country	Patent Number	Estimated Expiration
South Africa	201606912	⤷ Get Started Free
World Intellectual Property Organization (WIPO)	2015162175	⤷ Get Started Free
Uruguay	36094	⤷ Get Started Free
United States of America	2017044204	⤷ Get Started Free
Ukraine	115206	⤷ Get Started Free
Slovenia	3134537	⤷ Get Started Free
Singapore	11201608792X	⤷ Get Started Free
>Country	>Patent Number	>Estimated Expiration

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