Last Updated: October 22, 2026

Biologic Drugs With Established Pharmaceutical Class: CD38-directed Cytolytic Antibody

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Biologic Drugs With Established Pharmaceutical Class: CD38-directed Cytolytic Antibody

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Approval Date	Patent No.	Patent Expiration
Janssen Biotech, Inc.	DARZALEX	daratumumab	Injection	761036	2015-11-16	⤷ Start Trial	⤷ Start Trial
Janssen Biotech, Inc.	DARZALEX	daratumumab	Injection	761036	2015-11-16	7,829,673	⤷ Start Trial
Janssen Biotech, Inc.	DARZALEX	daratumumab	Injection	761036	2015-11-16	9,040,050	⤷ Start Trial
Janssen Biotech, Inc.	DARZALEX	daratumumab	Injection	761036	2015-11-16	9,187,565	⤷ Start Trial
Janssen Biotech, Inc.	DARZALEX	daratumumab	Injection	761036	2015-11-16	78,296,737,829,673	⤷ Start Trial
Janssen Biotech, Inc.	DARZALEX	daratumumab	Injection	761036	2015-11-16	90,400,509,040,050	⤷ Start Trial
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Approval Date	>Patent No.	>Patent Expiration

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