Absorption of Corticosteroids in Children With Juvenile Dermatomyositis
Completed
Ann & Robert H Lurie Children's Hospital of Chicago
Phase 2
1997-09-01
Juvenile dermatomyositis (JDM) is a connective tissue disease that causes skin rash and weak
muscles in children. The purpose of this study is to measure the absorption of oral
prednisolone and intravenous (IV) methylprednisolone and to determine levels of disease
activity indicators in the blood. These levels will be compared to see if there are patterns
specific to active and less active JDM.
Absorption of Corticosteroids in Children With Juvenile Dermatomyositis
Completed
Northwestern University
Phase 2
1997-09-01
Juvenile dermatomyositis (JDM) is a connective tissue disease that causes skin rash and weak
muscles in children. The purpose of this study is to measure the absorption of oral
prednisolone and intravenous (IV) methylprednisolone and to determine levels of disease
activity indicators in the blood. These levels will be compared to see if there are patterns
specific to active and less active JDM.
Study of Genotype and Phenotype Expression in Congenital Nephrogenic Diabetes Insipidus
Completed
Northwestern University
1995-09-01
OBJECTIVES:
I. Determine the relationship between genotype variations and clinical phenotype in patients
with congenital nephrogenic diabetes insipidus.
Study of Genotype and Phenotype Expression in Congenital Nephrogenic Diabetes Insipidus
Completed
National Center for Research Resources (NCRR)
1995-09-01
OBJECTIVES:
I. Determine the relationship between genotype variations and clinical phenotype in patients
with congenital nephrogenic diabetes insipidus.
Phase I Study of Human Von Willebrand Factor for Von Willebrand's Disease
Completed
University of North Carolina
Phase 1
1993-10-01
OBJECTIVES: I. Evaluate the effect of a new von Willebrand factor concentrate on bleeding
time, in vivo recovery, and circulating half-life of the infused factor in patients with von
Willebrand's disease.
II. Assess the safety of von Willebrand factor in these patients.
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