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Last Updated: April 19, 2024

CLINICAL TRIALS PROFILE FOR IBRITUMOMAB TIUXETAN


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All Clinical Trials for ibritumomab tiuxetan

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00017381 ↗ Monoclonal Antibody Therapy and Peripheral Stem Cell Transplant in Treating Patients With Non-Hodgkin's Lymphoma Completed National Cancer Institute (NCI) Early Phase 1 2001-04-01 This phase I trial is studying how well monoclonal antibody therapy with peripheral stem cell transplant works in treating patients with non-Hodgkin's lymphoma. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Peripheral stem cell transplant may allow the doctor to give higher doses of monoclonal antibodies and kill more cancer cells
NCT00038623 ↗ Study Of Yttrium-ibritumomab (Zevalin) For the Treatment Of Patients With Relapsed And Refractory Mantle Cell Lymphoma Completed Biogen Phase 2 2002-04-01 Study of Yttrium-ibritumomab (Zevalin) For the treatment of Patients with Relapsed & Refractory Mantle Cell Lymphoma
NCT00038623 ↗ Study Of Yttrium-ibritumomab (Zevalin) For the Treatment Of Patients With Relapsed And Refractory Mantle Cell Lymphoma Completed M.D. Anderson Cancer Center Phase 2 2002-04-01 Study of Yttrium-ibritumomab (Zevalin) For the treatment of Patients with Relapsed & Refractory Mantle Cell Lymphoma
NCT00058292 ↗ Radiolabeled Monoclonal Antibody Therapy and High-Dose Chemotherapy Followed By Autologous Peripheral Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma Completed National Cancer Institute (NCI) Phase 1 2000-04-01 RATIONALE: Radiolabeled monoclonal antibodies such as yttrium Y90 ibritumomab tiuxetan can locate cancer cells and deliver radioactive cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining yttrium Y90 ibritumomab tiuxetan and chemotherapy with autologous stem cell transplant may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: This phase I trial is studying how well giving yttrium Y90 ibritumomab tiuxetan with high-dose chemotherapy followed by autologous stem cell transplant work in treating patients with relapsed or refractory non-Hodgkin's lymphoma.
NCT00058292 ↗ Radiolabeled Monoclonal Antibody Therapy and High-Dose Chemotherapy Followed By Autologous Peripheral Stem Cell Transplant in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma Completed Northwestern University Phase 1 2000-04-01 RATIONALE: Radiolabeled monoclonal antibodies such as yttrium Y90 ibritumomab tiuxetan can locate cancer cells and deliver radioactive cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining yttrium Y90 ibritumomab tiuxetan and chemotherapy with autologous stem cell transplant may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: This phase I trial is studying how well giving yttrium Y90 ibritumomab tiuxetan with high-dose chemotherapy followed by autologous stem cell transplant work in treating patients with relapsed or refractory non-Hodgkin's lymphoma.
NCT00058422 ↗ Rituximab and Combination Chemotherapy Combined With Yttrium Y 90 Ibritumomab Tiuxetan in Treating Older Patients With Previously Untreated B-Cell Lymphoma Completed National Cancer Institute (NCI) Phase 2 2003-02-10 RATIONALE: Monoclonal antibodies such as rituximab and yttrium Y 90 ibritumomab tiuxetan can locate cancer cells and either kill them or deliver radioactive cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining rituximab and combination chemotherapy with yttrium Y 90 ibritumomab tiuxetan may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining rituximab and combination chemotherapy with yttrium Y 90 ibritumomab tiuxetan in treating older patients who have B-cell lymphoma that has not been previously treated.
NCT00058422 ↗ Rituximab and Combination Chemotherapy Combined With Yttrium Y 90 Ibritumomab Tiuxetan in Treating Older Patients With Previously Untreated B-Cell Lymphoma Completed Memorial Sloan Kettering Cancer Center Phase 2 2003-02-10 RATIONALE: Monoclonal antibodies such as rituximab and yttrium Y 90 ibritumomab tiuxetan can locate cancer cells and either kill them or deliver radioactive cancer-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining rituximab and combination chemotherapy with yttrium Y 90 ibritumomab tiuxetan may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combining rituximab and combination chemotherapy with yttrium Y 90 ibritumomab tiuxetan in treating older patients who have B-cell lymphoma that has not been previously treated.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ibritumomab tiuxetan

Condition Name

Condition Name for ibritumomab tiuxetan
Intervention Trials
Lymphoma 23
Non-Hodgkin's Lymphoma 7
Diffuse Large B-Cell Lymphoma 6
Recurrent Adult Diffuse Large Cell Lymphoma 5
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Condition MeSH

Condition MeSH for ibritumomab tiuxetan
Intervention Trials
Lymphoma 72
Lymphoma, Non-Hodgkin 32
Lymphoma, B-Cell 24
Lymphoma, Large B-Cell, Diffuse 17
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Clinical Trial Locations for ibritumomab tiuxetan

Trials by Country

Trials by Country for ibritumomab tiuxetan
Location Trials
United States 176
Italy 42
Spain 18
France 9
Canada 8
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Trials by US State

Trials by US State for ibritumomab tiuxetan
Location Trials
California 12
Illinois 11
Texas 11
New York 8
Minnesota 8
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Clinical Trial Progress for ibritumomab tiuxetan

Clinical Trial Phase

Clinical Trial Phase for ibritumomab tiuxetan
Clinical Trial Phase Trials
Phase 4 1
Phase 3 8
Phase 2 49
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Clinical Trial Status

Clinical Trial Status for ibritumomab tiuxetan
Clinical Trial Phase Trials
Completed 43
Terminated 14
Unknown status 8
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Clinical Trial Sponsors for ibritumomab tiuxetan

Sponsor Name

Sponsor Name for ibritumomab tiuxetan
Sponsor Trials
National Cancer Institute (NCI) 19
Bayer 9
Biogen 9
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Sponsor Type

Sponsor Type for ibritumomab tiuxetan
Sponsor Trials
Other 84
Industry 33
NIH 20
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