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Last Updated: November 28, 2021

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CLINICAL TRIALS PROFILE FOR COLLAGENASE CLOSTRIDIUM HISTOLYTICUM

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All Clinical Trials for collagenase clostridium histolyticum

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00261209 ↗ Collagenase in the Treatment of Zone II Flexor Tendon Adhesions in the Hand Completed Stony Brook University Phase 1/Phase 2 2005-01-01 The purpose of this study is to dissolve flexor tendon adhesions associated with failed tendon repair surgery.
NCT01229436 ↗ Treatment Of Dupuytren's Contracture With Collagenase Clostridium Histolyticum Injection (Xiapex) Completed Pfizer Phase 3 2010-12-01 This study will evaluate the impact of Xiapex treatment on the range of motion (ROM) of the affected fingers and the patient and physician reported treatment satisfaction and disease severity and their relation to ROM. Recovery to normal activities, recovery time (How long overall, time to use hand, time to return to work or daily activities, amount of work or daily activity time missed or reduced and affects on productivity and daily activities) will be assessed via patient diary. Use of concomitant analgesic medications will be recorded and total healthcare resource utilization (HCRU).
NCT01588353 ↗ Collagenase Option for Reduction of Dupuytren's Contracture in Japan Completed Asahi Kasei Pharma Corporation Phase 3 2012-05-01 To investigate the efficacy and safety of AK160 in patients with Dupuytren's Contracture. To determine plasma concentration after the first injection of AK160 in patients with Dupuytren's Contracture.
NCT01613313 ↗ A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma Completed Advance Biofactures Corporation Phase 2 2012-05-01 The purpose of this research is to evaluate the safest and most effective dose of a Food and Drug Administration (FDA) approved drug (XIAFLEX) in the treatment of lipoma (fatty tumors of varying sizes that occur commonly in the adult population). The fat in the lipoma is like normal fat except that it is enclosed in a balloon-like structure which is made of collagen (fibrous tissue). Treatment of the lipoma with an injection of XIAFLEX (a protein that breaks down collagen fibers) may dissolve the collagen/fibrous strands thereby decreasing the size of the lipoma or removing it.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for collagenase clostridium histolyticum

Condition Name

Condition Name for collagenase clostridium histolyticum
Intervention Trials
Dupuytren Contracture 4
Cellulite 2
Lipoma 2
Dupuytren's Contracture 2
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Condition MeSH

Condition MeSH for collagenase clostridium histolyticum
Intervention Trials
Dupuytren Contracture 8
Contracture 6
Penile Induration 4
Lipoma 2
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Clinical Trial Locations for collagenase clostridium histolyticum

Trials by Country

Trials by Country for collagenase clostridium histolyticum
Location Trials
United States 20
Finland 6
Canada 3
Spain 3
Italy 2
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Trials by US State

Trials by US State for collagenase clostridium histolyticum
Location Trials
Florida 6
New York 6
Utah 2
Arizona 1
Louisiana 1
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Clinical Trial Progress for collagenase clostridium histolyticum

Clinical Trial Phase

Clinical Trial Phase for collagenase clostridium histolyticum
Clinical Trial Phase Trials
Phase 4 7
Phase 3 4
Phase 2 7
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Clinical Trial Status

Clinical Trial Status for collagenase clostridium histolyticum
Clinical Trial Phase Trials
Completed 9
Recruiting 5
Unknown status 3
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Clinical Trial Sponsors for collagenase clostridium histolyticum

Sponsor Name

Sponsor Name for collagenase clostridium histolyticum
Sponsor Trials
Endo Pharmaceuticals 6
Advance Biofactures Corporation 3
Charitable Union for the Research and Education of Peyronie's Disease 2
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Sponsor Type

Sponsor Type for collagenase clostridium histolyticum
Sponsor Trials
Other 28
Industry 12
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