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Last Updated: April 19, 2024

CLINICAL TRIALS PROFILE FOR BRENTUXIMAB VEDOTIN


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All Clinical Trials for brentuximab vedotin

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00430846 ↗ Phase I Open-Label Dose Finding Study of SGN-35 for CD30 Positive Hematologic Malignancies Completed Seagen Inc. Phase 1 2006-11-01 Phase I study to define the safety profile and pharmacokinetic parameters of SGN-35 in patients with relapsed/refractory CD30-positive hematologic malignancies. This is a single-arm, open-label, Phase I dose escalation study designed to define the MTD, PK, immunogenicity and anti-tumor activity of SGN-35 in patients with relapsed/refractory CD30-positive hematologic malignancies.
NCT00430846 ↗ Phase I Open-Label Dose Finding Study of SGN-35 for CD30 Positive Hematologic Malignancies Completed Seattle Genetics, Inc. Phase 1 2006-11-01 Phase I study to define the safety profile and pharmacokinetic parameters of SGN-35 in patients with relapsed/refractory CD30-positive hematologic malignancies. This is a single-arm, open-label, Phase I dose escalation study designed to define the MTD, PK, immunogenicity and anti-tumor activity of SGN-35 in patients with relapsed/refractory CD30-positive hematologic malignancies.
NCT00649584 ↗ A Phase I Dose Escalation Study of SGN-35 Alone and in Combination With Gemcitabine for CD30-Positive Malignancies Terminated Seagen Inc. Phase 1 2008-03-01 This study will examine the safety profile of SGN-35 alone and in combination with gemcitabine. The study will test increasing doses of SGN-35 given weekly to small groups of patients.
NCT00649584 ↗ A Phase I Dose Escalation Study of SGN-35 Alone and in Combination With Gemcitabine for CD30-Positive Malignancies Terminated Seattle Genetics, Inc. Phase 1 2008-03-01 This study will examine the safety profile of SGN-35 alone and in combination with gemcitabine. The study will test increasing doses of SGN-35 given weekly to small groups of patients.
NCT00848926 ↗ A Pivotal Open-Label Trial of Brentuximab Vedotin for Hodgkin Lymphoma Completed Millennium Pharmaceuticals, Inc. Phase 2 2009-02-01 This is a single-arm, open-label, multicenter, pivotal clinical trial to evaluate the efficacy and safety of brentuximab vedotin (SGN-35) as a single agent in patients with relapsed or refractory Hodgkin lymphoma.
NCT00848926 ↗ A Pivotal Open-Label Trial of Brentuximab Vedotin for Hodgkin Lymphoma Completed Seagen Inc. Phase 2 2009-02-01 This is a single-arm, open-label, multicenter, pivotal clinical trial to evaluate the efficacy and safety of brentuximab vedotin (SGN-35) as a single agent in patients with relapsed or refractory Hodgkin lymphoma.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for brentuximab vedotin

Condition Name

Condition Name for brentuximab vedotin
Intervention Trials
Hodgkin Lymphoma 29
Lymphoma, Non-Hodgkin 9
Classical Hodgkin Lymphoma 9
Disease, Hodgkin 9
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Condition MeSH

Condition MeSH for brentuximab vedotin
Intervention Trials
Lymphoma 135
Hodgkin Disease 86
Lymphoma, T-Cell 34
Lymphoma, Non-Hodgkin 30
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Clinical Trial Locations for brentuximab vedotin

Trials by Country

Trials by Country for brentuximab vedotin
Location Trials
United States 774
Canada 43
Italy 35
Spain 34
France 27
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Trials by US State

Trials by US State for brentuximab vedotin
Location Trials
California 53
New York 49
Texas 47
Washington 31
Ohio 31
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Clinical Trial Progress for brentuximab vedotin

Clinical Trial Phase

Clinical Trial Phase for brentuximab vedotin
Clinical Trial Phase Trials
Phase 4 3
Phase 3 12
Phase 2 87
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Clinical Trial Status

Clinical Trial Status for brentuximab vedotin
Clinical Trial Phase Trials
Completed 45
Recruiting 42
Active, not recruiting 30
[disabled in preview] 42
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Clinical Trial Sponsors for brentuximab vedotin

Sponsor Name

Sponsor Name for brentuximab vedotin
Sponsor Trials
Seagen Inc. 63
Seattle Genetics, Inc. 53
National Cancer Institute (NCI) 31
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Sponsor Type

Sponsor Type for brentuximab vedotin
Sponsor Trials
Industry 172
Other 145
NIH 31
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