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Last Updated: April 23, 2024

CLINICAL TRIALS PROFILE FOR BEVACIZUMAB


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Biosimilar Clinical Trials for bevacizumab

This table shows clinical trials for biosimilars. See the next table for all clinical trials
Trial ID Title Status Sponsor Phase Start Date Summary
NCT02069704 ↗ Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients Completed Laboratorio Elea Phoenix S.A. Phase 1 2014-10-29 This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care.
NCT02069704 ↗ Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients Completed Laboratorio Elea S.A.C.I.F. y A. Phase 1 2014-10-29 This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care.
NCT02069704 ↗ Bioequivalence Study Bevacizumab Biosimilar (BEVZ92) Versus Bevacizumab (AVASTIN®) in First-line Treatment mCRC Patients Completed Libbs Farmacêutica LTDA Phase 1 2014-10-29 This is a multicenter, open label, randomized bioequivalence study of BEVZ92 (bevacizumab biosimilar) and Avastin® with 2 parallel arms to compare the pharmacokinetic (PK) profile of BEVZ92 and Avastin® in combination with FOLFOX (any) or FOLFIRI chemotherapy. FOLFOX (any) or FOLFIRI will be chosen as per investigator criteria based on the hospital standard of care.
>Trial ID >Title >Status >Phase >Start Date >Summary

All Clinical Trials for bevacizumab

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00006786 ↗ Combination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal Cancer Completed National Cancer Institute (NCI) Phase 2 2000-11-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bevacizumab may stop the growth of colorectal cancer by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus bevacizumab in treating patients who have advanced colorectal cancer.
NCT00006786 ↗ Combination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal Cancer Completed Eastern Cooperative Oncology Group Phase 2 2000-11-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Bevacizumab may stop the growth of colorectal cancer by stopping blood flow to the tumor. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy plus bevacizumab in treating patients who have advanced colorectal cancer.
NCT00015951 ↗ Bevacizumab, Cytarabine, and Mitoxantrone on Treating Patients With Hematologic Cancers Completed National Cancer Institute (NCI) Phase 2 2001-04-01 RATIONALE: Monoclonal antibodies such as bevacizumab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining monoclonal antibody therapy with chemotherapy may be an effective treatment for hematologic cancer. PURPOSE: Phase II trial to study the effectiveness of bevacizumab combined with cytarabine and mitoxantrone in treating patients who have hematologic cancer.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for bevacizumab

Condition Name

Condition Name for bevacizumab
Intervention Trials
Colorectal Cancer 212
Breast Cancer 136
Metastatic Colorectal Cancer 113
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Condition MeSH

Condition MeSH for bevacizumab
Intervention Trials
Colorectal Neoplasms 471
Carcinoma 267
Carcinoma, Non-Small-Cell Lung 265
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Clinical Trial Locations for bevacizumab

Trials by Country

Trials by Country for bevacizumab
Location Trials
United States 7,284
Italy 595
Spain 459
China 382
Canada 379
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Trials by US State

Trials by US State for bevacizumab
Location Trials
California 382
Texas 337
New York 300
Florida 281
Ohio 281
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Clinical Trial Progress for bevacizumab

Clinical Trial Phase

Clinical Trial Phase for bevacizumab
Clinical Trial Phase Trials
Phase 4 85
Phase 3 327
Phase 2/Phase 3 62
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Clinical Trial Status

Clinical Trial Status for bevacizumab
Clinical Trial Phase Trials
Completed 1139
Recruiting 333
Terminated 234
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Clinical Trial Sponsors for bevacizumab

Sponsor Name

Sponsor Name for bevacizumab
Sponsor Trials
Genentech, Inc. 328
National Cancer Institute (NCI) 314
Hoffmann-La Roche 190
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Sponsor Type

Sponsor Type for bevacizumab
Sponsor Trials
Other 2541
Industry 1395
NIH 332
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