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Last Updated: September 24, 2020

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CLINICAL TRIALS PROFILE FOR ALBUMIN (HUMAN)

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All Clinical Trials for albumin (human)

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000117 Intravenous Immunoglobulin Therapy in Optic Neuritis Completed National Eye Institute (NEI) Phase 3 1995-08-01 To determine whether high-dose intravenous immunoglobulin (IVIg) is more effective than placebo in restoring lost visual function (visual acuity) in optic neuritis (ON). To determine the time course of recovery following IVIg administration. If the reports of IVIg-associated clinical improvement occurring within 3 to 6 months following treatment can be confirmed, this would provide indirect evidence that IVIg may promote central nervous system (CNS) remyelination in optic neuritis and multiple sclerosis (MS).
NCT00000580 Interruption of Maternal-to-Infant Transmission of Hepatitis B by Means of Hepatitis B Immune Globulin Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1975-11-01 To evaluate whether hepatitis B immune globulin with a high level of antibody against the hepatitis B antigen would be capable of interrupting maternal-fetal transmission of hepatitis B virus, the single most important route of hepatitis spread in the entire Third World.
NCT00000582 Cooperative Study of Factor VIII Inhibitors Completed National Heart, Lung, and Blood Institute (NHLBI) Phase 3 1978-07-01 To test the efficacy of prothrombin complex concentrates (Factor IX) in the treatment of hemophiliac patients who had inhibitors to Factor VIII.
NCT00000720 A Double-Blind, Placebo-Controlled Trial To Evaluate Intravenous Gamma Globulin in Children With Symptomatic HIV Infection Receiving Zidovudine Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 3 1969-12-31 To evaluate the clinical, immunologic, and virologic effects of oral zidovudine (AZT) plus intravenous immunoglobulin (IVIG) versus AZT plus placebo (albumin). It is estimated that by 1991, there may be 10,000 to 20,000 HIV-infected children in the United States. HIV infection in children is most often associated with symptomatic disease and poor prognosis. Treatment with antiviral therapy may be effective in changing the course of disease and decreasing mortality in this vulnerable population. AZT treatment has been shown to decrease mortality and the frequency of opportunistic infections in certain adult AIDS patients; therefore, it is likely that children may also benefit from this antiviral therapy. In addition, bacterial infections are frequently found in HIV-infected children. Because pooled human serum immunoglobulin, another name for antibodies, is effective in reducing bacterial infection in patients with defects of immunity, it may reduce the rate of bacterial infection in HIV-infected children as well. In this study, AZT will be administered together with IVIG to determine safety, tolerance, and efficacy of the combined treatment.
NCT00001476 Gene Therapy for Chronic Granulomatous Diseases - Long-term Follow-up Completed National Institute of Allergy and Infectious Diseases (NIAID) Phase 1 1995-06-01 This protocol will follow patients who participated in NIAID's study Gene Therapy Approach for Chronic Granulomatous Diseases (95-I-0134). No further gene therapy treatments will be given under this protocol. However, because gene therapy is a new technology and involves a permanent change in the genetic code of some cells, patients who have had this treatment require long-term health monitoring. Participants will be asked to provide updated address and telephone information and the names of two contact persons, such as siblings or friends. Patients will be seen about once a year at the NIH Clinical Center to provide an update on their health status and donate a small blood sample (about 2 teaspoons), which will be frozen and stored. If a patient acquires a serious illness, such as cancer, his or her stored blood will be tested; another of blood or tissue sample may also be requested for further study. If a patient develops a medical problem that is thought possibly to be related to gene therapy, the illness will be investigated. The annual follow-up visits will continue indefinitely or until the patient declines to continue participation. Participants may also agree to store some of their blood future research on chronic granulomatous diseases and other medical conditions. Stored samples may be labeled with a code, such as a number, that only the study team can link with the patient. Any identifying information about the patient will be kept confidential as is permitted by law.
NCT00002689 Radiation Therapy Plus Chemotherapy in Treating Patients With Pancreatic Cancer Completed Center for Molecular Medicine Phase 2 1995-09-01 RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy combined with chemotherapy may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of brachytherapy followed by external-beam radiation therapy plus chemotherapy in treating patients who have pancreatic cancer that cannot be removed surgically.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for albumin (human)

Condition Name

Condition Name for albumin (human)
Intervention Trials
Breast Cancer 37
Diabetic Nephropathy 37
Hypertension 25
Diabetes Mellitus, Type 2 21
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Condition MeSH

Condition MeSH for albumin (human)
Intervention Trials
Kidney Diseases 93
Diabetes Mellitus 76
Diabetes Mellitus, Type 2 72
Breast Neoplasms 69
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Clinical Trial Locations for albumin (human)

Trials by Country

Trials by Country for albumin (human)
Location Trials
China 166
Canada 143
Italy 86
Spain 80
Australia 74
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Trials by US State

Trials by US State for albumin (human)
Location Trials
California 91
New York 87
Texas 72
Illinois 68
Florida 60
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Clinical Trial Progress for albumin (human)

Clinical Trial Phase

Clinical Trial Phase for albumin (human)
Clinical Trial Phase Trials
Phase 4 228
Phase 3 142
Phase 2/Phase 3 36
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Clinical Trial Status

Clinical Trial Status for albumin (human)
Clinical Trial Phase Trials
Completed 372
Recruiting 238
Not yet recruiting 184
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Clinical Trial Sponsors for albumin (human)

Sponsor Name

Sponsor Name for albumin (human)
Sponsor Trials
National Cancer Institute (NCI) 69
Celgene Corporation 30
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 22
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Sponsor Type

Sponsor Type for albumin (human)
Sponsor Trials
Other 1298
Industry 356
NIH 134
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