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Last Updated: July 24, 2024

CLINICAL TRIALS PROFILE FOR TNKASE


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All Clinical Trials for TNKASE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00121446 ↗ Which Therapy for Acute Heart Attacks? (The WEST Study) Completed Eli Lilly and Company Phase 2/Phase 3 2003-07-01 In the setting of acute myocardial infarction (heart attacks), the principle objective of the WEST Study is to compare the impact on clinical outcomes of 3 different treatment strategies. The first is using medical (drug) therapy alone with standard care. The second strategy is identical medical (drug) therapy as the first group combined with early heart catheterization (within 24 hours) for angiography and if required, intervention. The third treatment strategy is direct admission (within 3 hrs) to the heart catheterization lab for angioplasty. WEST patients will be enrolled at first medical contact (using emergency medical services, e.g. ambulance) if possible or through Emergency Departments in participating health care facilities.
NCT00121446 ↗ Which Therapy for Acute Heart Attacks? (The WEST Study) Completed Hoffmann-La Roche Phase 2/Phase 3 2003-07-01 In the setting of acute myocardial infarction (heart attacks), the principle objective of the WEST Study is to compare the impact on clinical outcomes of 3 different treatment strategies. The first is using medical (drug) therapy alone with standard care. The second strategy is identical medical (drug) therapy as the first group combined with early heart catheterization (within 24 hours) for angiography and if required, intervention. The third treatment strategy is direct admission (within 3 hrs) to the heart catheterization lab for angioplasty. WEST patients will be enrolled at first medical contact (using emergency medical services, e.g. ambulance) if possible or through Emergency Departments in participating health care facilities.
NCT00121446 ↗ Which Therapy for Acute Heart Attacks? (The WEST Study) Completed Sanofi Phase 2/Phase 3 2003-07-01 In the setting of acute myocardial infarction (heart attacks), the principle objective of the WEST Study is to compare the impact on clinical outcomes of 3 different treatment strategies. The first is using medical (drug) therapy alone with standard care. The second strategy is identical medical (drug) therapy as the first group combined with early heart catheterization (within 24 hours) for angiography and if required, intervention. The third treatment strategy is direct admission (within 3 hrs) to the heart catheterization lab for angioplasty. WEST patients will be enrolled at first medical contact (using emergency medical services, e.g. ambulance) if possible or through Emergency Departments in participating health care facilities.
NCT00121446 ↗ Which Therapy for Acute Heart Attacks? (The WEST Study) Completed University of Alberta Phase 2/Phase 3 2003-07-01 In the setting of acute myocardial infarction (heart attacks), the principle objective of the WEST Study is to compare the impact on clinical outcomes of 3 different treatment strategies. The first is using medical (drug) therapy alone with standard care. The second strategy is identical medical (drug) therapy as the first group combined with early heart catheterization (within 24 hours) for angiography and if required, intervention. The third treatment strategy is direct admission (within 3 hrs) to the heart catheterization lab for angioplasty. WEST patients will be enrolled at first medical contact (using emergency medical services, e.g. ambulance) if possible or through Emergency Departments in participating health care facilities.
NCT01580618 ↗ Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy Terminated Genentech, Inc. Phase 2/Phase 3 2008-01-01 The objective of the study is to determine the safety and efficacy of TNK infusion for the treatment of loculated pleural effusions in patients with known malignancy compared to normal saline infusion.
NCT01580618 ↗ Tenecteplase (TNK) for Loculated Pleural Effusions in Patients With Malignancy Terminated Kaiser Permanente Phase 2/Phase 3 2008-01-01 The objective of the study is to determine the safety and efficacy of TNK infusion for the treatment of loculated pleural effusions in patients with known malignancy compared to normal saline infusion.
NCT02180204 ↗ Tenecteplase Versus Alteplase in Ischemic Stroke Management (TALISMAN) Withdrawn Reza Behrouz, DO Phase 2/Phase 3 2015-01-01 This is a double-blind parallel arm randomized trial aimed to assess efficacy and safety of intravenous Tenecteplase compared to intravenous Alteplase in eligible patients who present with symptoms of acute ischemic stroke within 3 to 4.5 hours from onset.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for TNKASE

Condition Name

Condition Name for TNKASE
Intervention Trials
Myocardial Infarction 2
Stroke, Ischemic 1
Basilar Artery Occlusion 1
COVID 1
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Condition MeSH

Condition MeSH for TNKASE
Intervention Trials
Stroke 3
Myocardial Infarction 3
ST Elevation Myocardial Infarction 2
Ischemic Stroke 2
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Clinical Trial Locations for TNKASE

Trials by Country

Trials by Country for TNKASE
Location Trials
Canada 5
China 5
United States 4
Australia 4
France 1
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Trials by US State

Trials by US State for TNKASE
Location Trials
California 2
Ohio 1
Hawaii 1
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Clinical Trial Progress for TNKASE

Clinical Trial Phase

Clinical Trial Phase for TNKASE
Clinical Trial Phase Trials
Phase 4 2
Phase 3 2
Phase 2/Phase 3 4
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Clinical Trial Status

Clinical Trial Status for TNKASE
Clinical Trial Phase Trials
Terminated 2
Not yet recruiting 2
Recruiting 2
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Clinical Trial Sponsors for TNKASE

Sponsor Name

Sponsor Name for TNKASE
Sponsor Trials
Genentech, Inc. 3
Wuhan No. 1 Hospital (Wenhua Liu) 1
Boehringer Ingelheim 1
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Sponsor Type

Sponsor Type for TNKASE
Sponsor Trials
Other 15
Industry 7
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