Last Updated: August 12, 2026

CLINICAL TRIALS PROFILE FOR SANTYL


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All Clinical Trials for SANTYL

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00651820 ↗ Effect of Collagenase on Healing and Scarring Completed Healthpoint Phase 4 2008-04-01 A study to compare the rate of complete wound closure and quality of resulting scar at 3, 6 and 9 months, between dermatome-induced skin wounds treated with Collagenase Santyl Ointment versus vehicle alone.
NCT01056198 ↗ Santyl vs. Sharp Debridement of Diabetic Foot Wounds Completed Healthpoint Phase 4 2010-02-01 This study tests two different approaches to the removal of dead tissue from the surface of a wound.
NCT01143714 ↗ A Study to Look at the Effects of Four Weeks of Treatment on the Healing of Diabetic Foot Ulcers Completed Healthpoint Phase 4 2010-06-01 The purpose of this study is to assess the effect of four weeks of treatment with Santyl Ointment, compared to White Petrolatum, on the change from baseline in wound area of diabetic foot ulcers over four weeks, and on the proportion of subjects achieving complete wound closure within 12 weeks from initiation of treatment.
NCT01143727 ↗ Enzymatic Versus (vs) Autolytic Debridement of Diabetic Foot Ulcers Completed Healthpoint Phase 4 2010-07-01 This study compares two standard methods for cleaning the surface of wounds on the feet of patients with diabetes mellitus. The question being asked is whether inflammation of the wound affects the ability of one or both of the methods to work.
NCT01516463 ↗ Using Santyl or Bacitracin on Second Degree Burns Withdrawn Healthpoint Phase 4 2012-03-01 Subjects who have minor, second degree burns may be enrolled in this study. Subjects will receive either Santyl ointment or bacitracin ointment to apply to the burn until it heals. Bandages will be used to keep the burn covered while it heals. Second degree burns generally leave a scar. Once the burn heals, lotion and an appropriate bandage will be used to try to minimize the appearance of a scar. The study hypothesis is that burns treated with Santyl will have a better scar appearance than burns treated with bacitracin. Subjects enrolled in this study will make once a week visits to the University of Kansas Medical Center outpatient burn clinic until the burn heals. The burn will be assessed for healing at these visits. Once healed, visits to the clinic will be every 1-3 months for up to 1 year. At these visits, the appearance of the scar will be evaluated
NCT02131961 ↗ EZCast-DFU Study With Portal for Application of Topical Medications Completed University of Miami Phase 1 2014-10-01 This study is designed to evaluate the ability to modify a contact cast system so that topical medications can be applied daily to an underlying wound in patients with diabetic plantar ulcers. The modification of the cast will be done by making an opening where the wound is located in the contact cast system. A contact cast system is a device that will reduce the pressure in the area where the wound is located.
NCT02482948 ↗ MEDIHONEY® Gel Versus Collagenase for Wound Debridement Terminated Derma Sciences, Inc. N/A 2015-06-01 The purpose of this study is to compare how well two products, Active Leptospermum Honey (ALH) (MEDIHONEY® Gel) and Collagenase (Santyl®), in removing the nonviable (non living) tissue.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for SANTYL

Condition Name

Condition Name for SANTYL
Intervention Trials
Diabetic Foot Ulcers 3
Burn, Partial Thickness 2
Impaired Wound Healing 1
Scarring 1
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Condition MeSH

Condition MeSH for SANTYL
Intervention Trials
Diabetic Foot 4
Foot Ulcer 4
Ulcer 3
Burns 2
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Clinical Trial Locations for SANTYL

Trials by Country

Trials by Country for SANTYL
Location Trials
United States 14
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Trials by US State

Trials by US State for SANTYL
Location Trials
Texas 4
Florida 2
Pennsylvania 2
Massachusetts 1
Illinois 1
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Clinical Trial Progress for SANTYL

Clinical Trial Phase

Clinical Trial Phase for SANTYL
Clinical Trial Phase Trials
Phase 4 6
Phase 1 1
N/A 1
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Clinical Trial Status

Clinical Trial Status for SANTYL
Clinical Trial Phase Trials
Completed 5
Terminated 1
Withdrawn 1
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Clinical Trial Sponsors for SANTYL

Sponsor Name

Sponsor Name for SANTYL
Sponsor Trials
Healthpoint 6
University of Miami 1
Derma Sciences, Inc. 1
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Sponsor Type

Sponsor Type for SANTYL
Sponsor Trials
Industry 8
Other 2
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