Last Updated: June 10, 2026

CLINICAL TRIALS PROFILE FOR PERTUZUMAB


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Biosimilar Clinical Trials for Pertuzumab

This table shows clinical trials for biosimilars. See the next table for all clinical trials
Trial ID Title Status Sponsor Phase Start Date Summary
NCT03811418 ↗ A Study to Compare Pertuzumab + Trastuzumab + Vinorelbine vs. Placebo + Trastuzumab + Docetaxel in Previously Untreated HER2-positive Metastatic Breast Cancer Withdrawn Amgen Phase 3 2019-01-01 This is a randomized, open-label, two-arm, phase III trial in Germany to investigate whether vinorelbine-based triple combination presents a less toxic treatment option than docetaxel-based triple combination in patients with HER2-positive advanced breast cancer who have not previously received any systemic treatment in the metastatic setting. The primary objective of the study is to compare patient-reported quality of life in the two treatment arms. Patients will be followed-up for survival until death or end of study after at least 79 deaths occured in each arm, whatever comes first.
NCT03811418 ↗ A Study to Compare Pertuzumab + Trastuzumab + Vinorelbine vs. Placebo + Trastuzumab + Docetaxel in Previously Untreated HER2-positive Metastatic Breast Cancer Withdrawn Arbeitsgemeinschaft fur Internistische Onkologie Phase 3 2019-01-01 This is a randomized, open-label, two-arm, phase III trial in Germany to investigate whether vinorelbine-based triple combination presents a less toxic treatment option than docetaxel-based triple combination in patients with HER2-positive advanced breast cancer who have not previously received any systemic treatment in the metastatic setting. The primary objective of the study is to compare patient-reported quality of life in the two treatment arms. Patients will be followed-up for survival until death or end of study after at least 79 deaths occured in each arm, whatever comes first.
NCT03811418 ↗ A Study to Compare Pertuzumab + Trastuzumab + Vinorelbine vs. Placebo + Trastuzumab + Docetaxel in Previously Untreated HER2-positive Metastatic Breast Cancer Withdrawn iOMEDICO AG Phase 3 2019-01-01 This is a randomized, open-label, two-arm, phase III trial in Germany to investigate whether vinorelbine-based triple combination presents a less toxic treatment option than docetaxel-based triple combination in patients with HER2-positive advanced breast cancer who have not previously received any systemic treatment in the metastatic setting. The primary objective of the study is to compare patient-reported quality of life in the two treatment arms. Patients will be followed-up for survival until death or end of study after at least 79 deaths occured in each arm, whatever comes first.
>Trial ID >Title >Status >Phase >Start Date >Summary

All Clinical Trials for Pertuzumab

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00058539 ↗ Safety and Efficacy Study of Pertuzumab to Treat Castration-Resistant Prostate Cancer Completed Genentech, Inc. Phase 2 2003-04-01 The purpose of this study is to evaluate safety and efficacy of Omnitarg (Pertuzumab) on cancerous lesions in men with castration-resistant (hormone-refractory) prostate cancer.
NCT00058552 ↗ A Study to Evaluate the Effect of HER2 Activation on rhuMAb 2C4 (Pertuzumab) in Subjects With Advanced Ovarian Cancer Completed Genentech, Inc. Phase 2 2003-05-01 The purpose of this study is to determine if the study drug pertuzumab is effective in treating patients with advanced ovarian cancer that is refractory to, or has recurred following, prior chemotherapy.
NCT00063154 ↗ Safety and Effect of Pertuzumab in Patients With Advanced Non-Small Cell Lung Cancer, Which Has Progressed After Prior Chemotherapy Completed Genentech, Inc. Phase 2 2003-07-01 The purpose of this study is to determine if the study drug pertuzumab is effective in treating patients with advanced lung cancer that has recurred following prior chemotherapy.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for Pertuzumab

Condition Name

Condition Name for Pertuzumab
Intervention Trials
Breast Cancer 116
Her2-Positive Breast Cancer 57
Metastatic Breast Cancer 22
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Condition MeSH

Condition MeSH for Pertuzumab
Intervention Trials
Breast Neoplasms 238
Neoplasms 13
Carcinoma 12
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Clinical Trial Locations for Pertuzumab

Trials by Country

Trials by Country for Pertuzumab
Location Trials
Italy 224
Spain 174
China 141
Canada 105
Germany 87
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Trials by US State

Trials by US State for Pertuzumab
Location Trials
Texas 51
New York 47
California 45
Florida 40
Massachusetts 39
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Clinical Trial Progress for Pertuzumab

Clinical Trial Phase

Clinical Trial Phase for Pertuzumab
Clinical Trial Phase Trials
PHASE4 3
PHASE3 8
PHASE2 29
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Clinical Trial Status

Clinical Trial Status for Pertuzumab
Clinical Trial Phase Trials
RECRUITING 102
Completed 65
Not yet recruiting 52
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Clinical Trial Sponsors for Pertuzumab

Sponsor Name

Sponsor Name for Pertuzumab
Sponsor Trials
Hoffmann-La Roche 52
Genentech, Inc. 37
National Cancer Institute (NCI) 17
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Sponsor Type

Sponsor Type for Pertuzumab
Sponsor Trials
Other 306
Industry 208
NIH 17
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