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Last Updated: March 19, 2024

CLINICAL TRIALS PROFILE FOR ONCASPAR


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All Clinical Trials for ONCASPAR

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002812 ↗ Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia Completed National Cancer Institute (NCI) Phase 3 1996-09-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug and giving the drugs in different combinations may kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of standard combination chemotherapy treatment with more intensive combination chemotherapy in treating children with acute lymphocytic leukemia.
NCT00002812 ↗ Combination Chemotherapy in Treating Children With Acute Lymphocytic Leukemia Completed Children's Oncology Group Phase 3 1996-09-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug and giving the drugs in different combinations may kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of standard combination chemotherapy treatment with more intensive combination chemotherapy in treating children with acute lymphocytic leukemia.
NCT00005945 ↗ Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia Completed National Cancer Institute (NCI) Phase 3 2000-06-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Giving more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating childhood acute lymphoblastic leukemia. PURPOSE: This randomized phase III trial is comparing different combination chemotherapy regimens to see how well they work in treating children with acute lymphoblastic leukemia.
NCT00005945 ↗ Comparison of Different Combination Chemotherapy Regimens in Treating Children With Acute Lymphoblastic Leukemia Completed Children's Oncology Group Phase 3 2000-06-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Giving more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating childhood acute lymphoblastic leukemia. PURPOSE: This randomized phase III trial is comparing different combination chemotherapy regimens to see how well they work in treating children with acute lymphoblastic leukemia.
NCT00016302 ↗ Combination Chemotherapy in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Completed National Cancer Institute (NCI) N/A 2001-04-01 Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. This phase II trial is studying several different combination chemotherapy regimens to see how well they work in treating patients with newly diagnosed acute lymphoblastic leukemia
NCT00022737 ↗ Combination Chemotherapy With or Without Peripheral Stem Cell Transplant in Treating Children With Acute Lymphoblastic Leukemia Completed National Cancer Institute (NCI) Phase 3 2002-10-01 This phase II trial is studying how well combination chemotherapy with or without donor peripheral stem cell transplant works in treating children with acute lymphoblastic leukemia. Giving combination chemotherapy before a donor peripheral stem cell transplant helps stop the growth of cancer cells. It also helps stop the patient's immune system from rejecting the donor's stem cells. When the healthy stem cells from a donor are infused into the patient they may help the patient's bone marrow make stem cells, red blood cells, white blood cells, and platelets.
NCT00075725 ↗ Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia Completed National Cancer Institute (NCI) Phase 3 2003-12-29 This randomized phase III trial is studying dexamethasone to see how well it works compared to prednisone during induction therapy. This trial is also studying methotrexate and leucovorin calcium to see how well they work compared to methotrexate alone during maintenance therapy in treating patients with newly diagnosed acute lymphoblastic leukemia (ALL). Drugs used in chemotherapy, such as dexamethasone, prednisone, methotrexate, and leucovorin calcium, work in different ways to stop cancer cells from dividing so they stop growing or die. Giving more than one drug may kill more cancer cells. It is not yet known which combination chemotherapy regimen is more effective in treating acute lymphoblastic leukemia.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for ONCASPAR

Condition Name

Condition Name for ONCASPAR
Intervention Trials
Acute Lymphoblastic Leukemia 17
Untreated Childhood Acute Lymphoblastic Leukemia 11
Untreated Adult Acute Lymphoblastic Leukemia 9
B Acute Lymphoblastic Leukemia 8
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Condition MeSH

Condition MeSH for ONCASPAR
Intervention Trials
Precursor Cell Lymphoblastic Leukemia-Lymphoma 48
Leukemia 48
Leukemia, Lymphoid 47
Lymphoma 22
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Clinical Trial Locations for ONCASPAR

Trials by Country

Trials by Country for ONCASPAR
Location Trials
Canada 144
Australia 60
New Zealand 25
Puerto Rico 14
Switzerland 9
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Trials by US State

Trials by US State for ONCASPAR
Location Trials
Texas 34
California 33
New York 30
Pennsylvania 28
Ohio 28
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Clinical Trial Progress for ONCASPAR

Clinical Trial Phase

Clinical Trial Phase for ONCASPAR
Clinical Trial Phase Trials
Phase 4 1
Phase 3 20
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for ONCASPAR
Clinical Trial Phase Trials
Completed 22
Active, not recruiting 12
Recruiting 11
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Clinical Trial Sponsors for ONCASPAR

Sponsor Name

Sponsor Name for ONCASPAR
Sponsor Trials
National Cancer Institute (NCI) 33
Children's Oncology Group 16
M.D. Anderson Cancer Center 6
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Sponsor Type

Sponsor Type for ONCASPAR
Sponsor Trials
Other 46
NIH 33
Industry 16
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