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Last Updated: April 26, 2024

CLINICAL TRIALS PROFILE FOR GAZYVA


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All Clinical Trials for GAZYVA

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01995669 ↗ Lenalidomide and Obinutuzumab in Treating Patients With Relapsed Indolent Non-Hodgkin Lymphoma Active, not recruiting Celgene Phase 1/Phase 2 2014-05-21 This phase I/II trial studies the side effects and best dose of lenalidomide when given together with obinutuzumab and how well this combination works in treating patients with low-grade non-Hodgkin lymphoma (NHL) that has returned after a period of improvement (relapsed). Biological therapies, such as lenalidomide, may attack specific cancer cells and stop them from growing or kill them. Obinutuzumab is a form of targeted therapy because it attaches itself to specific molecules (receptors) on the surface of cancer cells, known as CD20 receptors. When obinutuzumab attaches to CD20 receptors, the signals that tell the cells to grow are blocked and the cancer cell may be marked for destruction by the body's immune system. Giving lenalidomide and obinutuzumab together may work better in treating NHL.
NCT01995669 ↗ Lenalidomide and Obinutuzumab in Treating Patients With Relapsed Indolent Non-Hodgkin Lymphoma Active, not recruiting Genentech, Inc. Phase 1/Phase 2 2014-05-21 This phase I/II trial studies the side effects and best dose of lenalidomide when given together with obinutuzumab and how well this combination works in treating patients with low-grade non-Hodgkin lymphoma (NHL) that has returned after a period of improvement (relapsed). Biological therapies, such as lenalidomide, may attack specific cancer cells and stop them from growing or kill them. Obinutuzumab is a form of targeted therapy because it attaches itself to specific molecules (receptors) on the surface of cancer cells, known as CD20 receptors. When obinutuzumab attaches to CD20 receptors, the signals that tell the cells to grow are blocked and the cancer cell may be marked for destruction by the body's immune system. Giving lenalidomide and obinutuzumab together may work better in treating NHL.
NCT01995669 ↗ Lenalidomide and Obinutuzumab in Treating Patients With Relapsed Indolent Non-Hodgkin Lymphoma Active, not recruiting National Cancer Institute (NCI) Phase 1/Phase 2 2014-05-21 This phase I/II trial studies the side effects and best dose of lenalidomide when given together with obinutuzumab and how well this combination works in treating patients with low-grade non-Hodgkin lymphoma (NHL) that has returned after a period of improvement (relapsed). Biological therapies, such as lenalidomide, may attack specific cancer cells and stop them from growing or kill them. Obinutuzumab is a form of targeted therapy because it attaches itself to specific molecules (receptors) on the surface of cancer cells, known as CD20 receptors. When obinutuzumab attaches to CD20 receptors, the signals that tell the cells to grow are blocked and the cancer cell may be marked for destruction by the body's immune system. Giving lenalidomide and obinutuzumab together may work better in treating NHL.
NCT01995669 ↗ Lenalidomide and Obinutuzumab in Treating Patients With Relapsed Indolent Non-Hodgkin Lymphoma Active, not recruiting M.D. Anderson Cancer Center Phase 1/Phase 2 2014-05-21 This phase I/II trial studies the side effects and best dose of lenalidomide when given together with obinutuzumab and how well this combination works in treating patients with low-grade non-Hodgkin lymphoma (NHL) that has returned after a period of improvement (relapsed). Biological therapies, such as lenalidomide, may attack specific cancer cells and stop them from growing or kill them. Obinutuzumab is a form of targeted therapy because it attaches itself to specific molecules (receptors) on the surface of cancer cells, known as CD20 receptors. When obinutuzumab attaches to CD20 receptors, the signals that tell the cells to grow are blocked and the cancer cell may be marked for destruction by the body's immune system. Giving lenalidomide and obinutuzumab together may work better in treating NHL.
NCT02100852 ↗ TGR-1202, a PI3K Delta Inhibitor, in Combination With Obinutuzumab and Chlorambucil in Patients With Chronic Lymphocytic Leukemia (CLL) Completed TG Therapeutics, Inc. Phase 1 2014-03-12 The purpose of this study is to evaluate the safety and effectiveness of TGR-1202 in combination with obinutuzumab (Gazyva) and chlorambucil in patients with chronic lymphocytic leukemia.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for GAZYVA

Condition Name

Condition Name for GAZYVA
Intervention Trials
Chronic Lymphocytic Leukemia 20
Small Lymphocytic Lymphoma 11
Grade 3a Follicular Lymphoma 9
Grade 1 Follicular Lymphoma 7
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Condition MeSH

Condition MeSH for GAZYVA
Intervention Trials
Lymphoma 38
Leukemia, Lymphocytic, Chronic, B-Cell 33
Leukemia, Lymphoid 32
Leukemia 30
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Clinical Trial Locations for GAZYVA

Trials by Country

Trials by Country for GAZYVA
Location Trials
United States 355
Italy 24
Spain 18
Australia 18
Japan 16
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Trials by US State

Trials by US State for GAZYVA
Location Trials
Texas 23
California 18
New York 17
Ohio 13
Massachusetts 12
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Clinical Trial Progress for GAZYVA

Clinical Trial Phase

Clinical Trial Phase for GAZYVA
Clinical Trial Phase Trials
Phase 3 9
Phase 2 38
Phase 1/Phase 2 8
[disabled in preview] 17
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Clinical Trial Status

Clinical Trial Status for GAZYVA
Clinical Trial Phase Trials
Recruiting 35
Not yet recruiting 12
Active, not recruiting 12
[disabled in preview] 10
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Clinical Trial Sponsors for GAZYVA

Sponsor Name

Sponsor Name for GAZYVA
Sponsor Trials
Genentech, Inc. 20
National Cancer Institute (NCI) 19
M.D. Anderson Cancer Center 9
[disabled in preview] 13
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Sponsor Type

Sponsor Type for GAZYVA
Sponsor Trials
Other 77
Industry 63
NIH 19
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