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Last Updated: March 28, 2024

CLINICAL TRIALS PROFILE FOR EMGALITY


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All Clinical Trials for EMGALITY

Trial ID Title Status Sponsor Phase Start Date Summary
NCT04271202 ↗ Novel Insight Into Migraine Pathophysiolgy and Galcanezumab Mechanisms of Action Recruiting Eli Lilly and Company Phase 4 2020-07-29 The purpose of this study is to understand better the mechanisms of action of calcitonin gene related peptide (CGRP) targeted monoclonal antibodies in migraine prevention. Specifically, the protocol will allow the investigators to determine whether the main site of action of this novel and recently-approved class of migraine prophylactic drugs act inside or outside the brain and if so, where.
NCT04271202 ↗ Novel Insight Into Migraine Pathophysiolgy and Galcanezumab Mechanisms of Action Recruiting Beth Israel Deaconess Medical Center Phase 4 2020-07-29 The purpose of this study is to understand better the mechanisms of action of calcitonin gene related peptide (CGRP) targeted monoclonal antibodies in migraine prevention. Specifically, the protocol will allow the investigators to determine whether the main site of action of this novel and recently-approved class of migraine prophylactic drugs act inside or outside the brain and if so, where.
NCT04417361 ↗ Galcanezumab for Vestibular Migraine Recruiting Eli Lilly and Company Phase 2 2020-09-18 Vestibular migraine (VM) has been recognized a distinct subtype of migraine that causes dizziness as the predominant symptom. Criteria for diagnosis have been adopted by the Barany Society. Previous epidemiological research from the investigators has shown that VM affects 2.7% of the adult population of the United States. Yet, despite its high prevalence, there is very little data upon which to guide treatment decisions. A Cochrane review in 2015 concluded that there were no placebo controlled trials in VM, and none have been done since then. The investigators recently developed and validated a patient reported outcome tool for VM called VM-PATHI (VM- Patient Assessment Tool and Handicap Inventory). Anecdotal evidence suggests that CGRP antagonists, such as Galcanezumab, may be effective in reducing or eliminating symptoms in VM. Therefore, the investigators propose a pilot study of changes in VM-PATHI scores, comparing active treatment (Galcanezumab) to placebo arms.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for EMGALITY

Condition Name

Condition Name for EMGALITY
Intervention Trials
Chronic Migraine 1
Chronic Migraine, Headache 1
Headache, Migraine 1
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Condition MeSH

Condition MeSH for EMGALITY
Intervention Trials
Migraine Disorders 4
Headache 2
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Clinical Trial Locations for EMGALITY

Trials by Country

Trials by Country for EMGALITY
Location Trials
United States 4
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Trials by US State

Trials by US State for EMGALITY
Location Trials
Illinois 2
California 1
Massachusetts 1
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Clinical Trial Progress for EMGALITY

Clinical Trial Phase

Clinical Trial Phase for EMGALITY
Clinical Trial Phase Trials
Phase 4 3
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for EMGALITY
Clinical Trial Phase Trials
Recruiting 3
Not yet recruiting 1
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Clinical Trial Sponsors for EMGALITY

Sponsor Name

Sponsor Name for EMGALITY
Sponsor Trials
Chicago Headache Center & Research Institute 2
Eli Lilly and Company 2
Beth Israel Deaconess Medical Center 1
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Sponsor Type

Sponsor Type for EMGALITY
Sponsor Trials
Other 4
Industry 3
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