Details for Patent: 8,669,273
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Which drugs does patent 8,669,273 protect, and when does it expire?
Patent 8,669,273 protects NERLYNX and is included in one NDA.
This patent has thirty-seven patent family members in twenty-five countries.
Summary for Patent: 8,669,273
| Title: | Antineoplastic combinations of 4-anilino-3-cyanoquinolines and capecitabine |
| Abstract: | A combination of a 4-anilino-3-cyanoquinoline compound (e.g. HKI-272, SKI-606, EKB-569) and a capecitabine compound in the treatment of a neoplasm is provided. Regimens, kits, and methods for treatment of neoplasm, including breast cancer including metastatic breast cancer, and lung cancer, using this combination, optionally in combination with other anti-neoplastic agents, or immune modulators are also described. |
| Inventor(s): | Zacharchuk; Charles Michael (Westford, MA), Quinn; Susan Elizabeth (Norwood, MA), Wang; Kenneth Kuan-Yuen (Waltham, MA), Binlich; Florence Marie Helene (Ville d'Avray, FR) |
| Assignee: | Wyeth LLC (Madison, NJ) |
| Application Number: | 12/534,895 |
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Patent Claim Types: see list of patent claims | Use; Delivery; |
Drugs Protected by US Patent 8,669,273
| Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Puma Biotech | NERLYNX | neratinib maleate | TABLET;ORAL | 208051-001 | Jul 17, 2017 | RX | Yes | Yes | ⤷ Try a Trial | ⤷ Try a Trial | USE IN COMBINATION WITH CAPECITABINE, FOR THE TREATMENT OF ADULT PATIENTS WITH ADVANCED OR METASTATIC HER2-POSITIVE BREAST CANCER WHO HAVE RECEIVED TWO OR MORE PRIOR ANTI-HER2 BASED REGIMENS IN THE METASTATIC SETTING | ⤷ Try a Trial | ||||
| >Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
International Family Members for US Patent 8,669,273
| Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
|---|---|---|---|---|---|
| Australia | 2009279771 | ⤷ Try a Trial | |||
| Brazil | PI0916694 | ⤷ Try a Trial | |||
| Canada | 2730715 | ⤷ Try a Trial | |||
| China | 102202667 | ⤷ Try a Trial | |||
| >Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |
