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Last Updated: May 18, 2024

Details for Patent: 8,357,693

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Which drugs does patent 8,357,693 protect, and when does it expire?

Patent 8,357,693 protects REZUROCK and is included in one NDA.

This patent has twenty-two patent family members in nineteen countries.

Summary for Patent: 8,357,693

Title:	Pharmacokinetically improved compounds
Abstract:	The present invention relates to inhibitors of ROCK1 and ROCK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and or ROCK2 that are useful for the treatment of disease.
Inventor(s):	Bartolozzi; Alessandra (Somerville, MA), Campbell; Stewart (Framingham, MA), Foudoulakis; Hope (Framingham, MA), Kirk; Brian (Sudbury, MA), Ram; Siya (Winchester, MA), Sweetnam; Paul (Marblehead, MA)
Assignee:	Surface Logix, Inc. (Brighton, MA)
Application Number:	11/887,218
Patent Claim Types: see list of patent claims	Use; Composition; Compound;

Drugs Protected by US Patent 8,357,693

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Applicant	Tradename	Generic Name	Dosage	NDA	Approval Date	TE	Type	RLD	RS	Patent No.	Patent Expiration	Product	Substance	Delist Req.	Patented / Exclusive Use	Submissiondate
Kadmon Pharms Llc	REZUROCK	belumosudil mesylate	TABLET;ORAL	214783-001	Jul 16, 2021		RX	Yes	Yes	⤷ Try a Trial	⤷ Try a Trial	Y	Y		FOR THE TREATMENT OF CHRONIC GRAFT VERSUS HOLD DISEASE	⤷ Try a Trial
>Applicant	>Tradename	>Generic Name	>Dosage	>NDA	>Approval Date	>TE	>Type	>RLD	>RS	>Patent No.	>Patent Expiration	>Product	>Substance	>Delist Req.	>Patented / Exclusive Use	>Submissiondate

Foreign Priority and PCT Information for Patent: 8,357,693

PCT Information
PCT Filed	March 27, 2006	PCT Application Number:	PCT/US2006/011271
PCT Publication Date:	October 05, 2006	PCT Publication Number:	WO2006/105081

International Family Members for US Patent 8,357,693

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Country	Patent Number	Estimated Expiration	Supplementary Protection Certificate	SPC Country	SPC Expiration
Australia	2006230159	⤷ Try a Trial
Brazil	PI0622285	⤷ Try a Trial
Canada	2602254	⤷ Try a Trial
>Country	>Patent Number	>Estimated Expiration	>Supplementary Protection Certificate	>SPC Country	>SPC Expiration

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