Details for Patent: 10,543,274
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Which drugs does patent 10,543,274 protect, and when does it expire?
Patent 10,543,274 protects PEPAXTO and is included in one NDA.
This patent has sixty-four patent family members in twenty-eight countries.
Summary for Patent: 10,543,274
Title: | Lyophilized preparation of cytotoxic dipeptides |
Abstract: | The present invention is directed to novel lyophilized pharmaceutical preparations comprising a cytotoxic dipeptides such as melphalan flufenamide and one or more excipient(s) selected from the group comprising a polysorbate; a polyethylene glycol; .beta.-cyclodextrin; ocyclodextrin; hydroxypropyl-.beta.-cyclodextrin; sulfobutylether-.beta.-cyclodextrin; lactose; benzyl alcohol; disodium succinate; propylene glycol; Cremophor EL; Dimethyl sulfoxide; D-mannitol; Trehalose; Sucrose and an amino acid. This preparation may be further formulated and is useful in cancer therapy. |
Inventor(s): | Spira; Jack (Tyreso, SE), Lehmann; Fredrik (Knivsta, SE) |
Assignee: | ONCOPEPTIDES AB (Stockholm, SE) |
Application Number: | 16/382,276 |
Patent Claim Types: see list of patent claims | Use; Composition; Formulation; |
Drugs Protected by US Patent 10,543,274
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oncopeptides Ab | PEPAXTO | melphalan flufenamide hydrochloride | POWDER;INTRAVENOUS | 214383-001 | Feb 26, 2021 | DISCN | Yes | No | ⤷ Try a Trial | ⤷ Try a Trial | IN COMBINATION WITH DEXAMETHASONE TO TREAT RELAPSED OR REFRACTORY MULTIPLE MYELOMA (REFACTORY TO AT LEAST 1 PROTEASOME INHIBITOR, 1 IMMUNOMODULATORY AGENT, AND 1 ANTI-CD38 MAB) IN ADULTS WHO RECEIVED AT LEAST 4 PRIOR LINES OF THERAPY | ⤷ Try a Trial | ||||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 10,543,274
Foriegn Application Priority Data | ||
Foreign Country | Foreign Patent Number | Foreign Patent Date |
Sweden | 1150371 | Apr 28, 2011 |
International Family Members for US Patent 10,543,274
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Australia | 2012247545 | ⤷ Try a Trial | |||
Brazil | 112013027584 | ⤷ Try a Trial | |||
Canada | 2833500 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |