Details for Patent: 10,119,143
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Which drugs does patent 10,119,143 protect, and when does it expire?
Patent 10,119,143 protects GIVLAARI and is included in one NDA.
This patent has seventy patent family members in thirty-seven countries.
Summary for Patent: 10,119,143
Title: | Compositions and methods for inhibiting expression of the ALAS1 gene |
Abstract: | The invention relates to double-stranded ribonucleic acid (dsRNA) compositions targeting the ALAS1 gene, and methods of using such dsRNA compositions to alter (e.g., inhibit) expression of ALAS1. |
Inventor(s): | Bettencourt; Brian (Groton, MA), Fitzgerald; Kevin (Brookline, MA), Querbes; William (Cambridge, MA), Desnick; Robert J. (New York, NY), Yasuda; Makiko (New York, NY) |
Assignee: | ALNYLAM PHARMACEUTICALS, INC. (Cambridge, MA) ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (New York, NY) |
Application Number: | 15/027,176 |
Patent Claim Types: see list of patent claims | Use; Composition; Compound; |
Drugs Protected by US Patent 10,119,143
Applicant | Tradename | Generic Name | Dosage | NDA | Approval Date | TE | Type | RLD | RS | Patent No. | Patent Expiration | Product | Substance | Delist Req. | Patented / Exclusive Use | Submissiondate |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alnylam Pharms Inc | GIVLAARI | givosiran sodium | SOLUTION;SUBCUTANEOUS | 212194-001 | Nov 20, 2019 | RX | Yes | Yes | ⤷ Try a Trial | ⤷ Try a Trial | Y | Y | TREATMENT OF ACUTE HEPATIC PORPHYRIA | ⤷ Try a Trial | ||
>Applicant | >Tradename | >Generic Name | >Dosage | >NDA | >Approval Date | >TE | >Type | >RLD | >RS | >Patent No. | >Patent Expiration | >Product | >Substance | >Delist Req. | >Patented / Exclusive Use | >Submissiondate |
Foreign Priority and PCT Information for Patent: 10,119,143
PCT Information | |||
PCT Filed | October 03, 2014 | PCT Application Number: | PCT/US2014/059160 |
PCT Publication Date: | April 09, 2015 | PCT Publication Number: | WO2015/051318 |
International Family Members for US Patent 10,119,143
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
---|---|---|---|---|---|
Argentina | 097920 | ⤷ Try a Trial | |||
Argentina | 118658 | ⤷ Try a Trial | |||
Australia | 2014331604 | ⤷ Try a Trial | |||
Australia | 2020286311 | ⤷ Try a Trial | |||
Australia | 2023266354 | ⤷ Try a Trial | |||
Brazil | 112016007226 | ⤷ Try a Trial | |||
Brazil | 122020001264 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |