Details for Patent: 9,663,528
✉ Email this page to a colleague
Title: | Substituted 1,2,3,4,6,8,12,12a-octahydro-1,4-methanodipyrido[1,2-a:1',2'-d]pyrazines and methods for treating viral infections |
Abstract: | Compounds for use in the treatment of human immunodeficiency virus (HIV) infection are disclosed. The compounds have the following Formula (I): ##STR00001## including stereoisomers and pharmaceutically acceptable salts thereof, wherein R.sup.1, X, W, Y.sup.1, Y.sup.2, Z.sup.1, and Z.sup.4 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed. |
Inventor(s): | Desai; Manoj C. (Foster City, CA), Jin; Haolun (Foster City, CA), Lazerwith; Scott E. (Burlingame, CA), Pyun; Hyung-Jung (Fremont, CA), Taylor; James G. (Burlingame, CA) |
Assignee: | Gilead Sciences, Inc. (Foster City, CA) |
Filing Date: | Jul 31, 2015 |
Application Number: | 14/815,504 |
Claims: | 1. A compound which is: ##STR00148## or a pharmaceutically acceptable salt thereof. 2. A pharmaceutical composition comprising a compound which is: ##STR00149## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent or excipient. 3. A compound which is: ##STR00150## or a pharmaceutically acceptable salt thereof. 4. A pharmaceutical composition comprising a compound which is: ##STR00151## or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, diluent or excipient. |