Details for Patent: 6,872,838
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Title: | Water soluble prodrugs of hindered alcohols |
Abstract: | The present invention is directed to novel water-soluble prodrugs of aliphatic or aromatic hindered hydroxyl group containing pharmaceuticals. |
Inventor(s): | Stella; Valentino J. (Lawrence, KS), Zygmunt; Jan J. (Longmont, CO), Georg; Ingrid Gunda (Lawrence, KS), Safadi; Muhammad S. (Nazareth, IL) |
Assignee: | University of Kansas (Lawrence, KS) |
Filing Date: | Jul 29, 2002 |
Application Number: | 10/208,647 |
Claims: | 1. A compound selected from the group consisting of O-phosphonoxymethylpropofol Dibenzy ester, O-phosphonoxymethyl-alpha-tocopherol Dibenzyl ester, and 4'-O-phosphonooxymethyletopside Dibenzyl ester. 2. A compound selected from the group consisting of O-phosphonoxymethylpropofol Disodium salt, O-phosphonoxymethyl-alpha-tocopherol Disodium salt, and 4'-O-phosphonoxymethyletoposide Disodium salt. |