Details for Patent: 5,869,641
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Title: | High affinity nucleic acid ligands of CD4 |
Abstract: | Methods are described for the identification and preparation of high-affinity nucleic acid ligands to CD4. Included in the invention are specific 2'F RNA ligands to CD4 identified by the SELEX method. |
Inventor(s): | Jayasena; Sumedha (Boulder, CO), Davis; Kenneth A. (Woodside, CA), Gold; Larry (Boulder, CO) |
Assignee: | NeXstar Pharmaceuticals, Inc. (Boulder, CO) |
Filing Date: | Feb 14, 1997 |
Application Number: | 08/799,949 |
Claims: | 1. A purified and isolated non-naturally occurring nucleic acid ligand to CD4, wherein said ligand is an RNA selected from the group consisting of the sequences set forth in Table 2 (SEQ ID NOS:7-24). |