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Last Updated: May 16, 2024

Claims for Patent: 9,833,448


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Summary for Patent: 9,833,448
Title:Piperidinone carboxamide azaindane CGRP receptor antagonists
Abstract: The present invention is directed to piperidinone carboxamide azaindane derivatives which are antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as migraine. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
Inventor(s): Bell; Ian M. (Harleysville, PA), Fraley; Mark E. (North Wales, PA), Gallicchio; Steven N. (Horsham, PA), Ginnetti; Anthony (Perkasie, PA), Mitchell; Helen J. (Richboro, PA), Paone; Daniel V. (Lansdale, PA), Staas; Donnette D. (Harleysville, PA), Wang; Cheng (Fort Washington, PA), Zartman; C. Blair (Hatfield, PA)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:15/293,569
Patent Claims: 1. A method of treating migraine in a mammalian patient in need of such treatment which method comprises administering to the patient a therapeutically effective amount of a pharmaceutical composition comprising the compound of Formula II: ##STR00053## or a pharmaceutically acceptable salt thereof.

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