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Last Updated: May 6, 2024

Claims for Patent: 4,435,449

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Summary for Patent: 4,435,449

Title:	Treatment of minimal brain dysfunction (MBD)
Abstract:	A method of Treatment of Minimal Brain Dysfunction (MBD) also known as ATTENTION DEFICIT DISORDER in humans by the administration of the compound of the formula I ##STR1## or a pharmaceutically acceptable acid addition salt thereof in a non-toxic, effective therapeutic amount (calculated as base) to a human in need thereof.
Inventor(s):	Stern; Warren C. (Raleigh, NC)
Assignee:	Burroughs Wellcome Co. (Research Triangle Park, NC)
Application Number:	06/395,147
Patent Claims:	1. A method of treating minimal brain dysfunction in a human suffering from same, which comprises administering to said human an effective non-toxic minimal brain dysfunction amount of a compound of the formula (I) ##STR3## or a pharmaceutically acceptable acid addition salt thereof. 2. The method of claim 1 in which a pharmaceutically acceptable acid addition salt thereof is administered. 3. The method of claim 2 in which the salt is the hydrochloride salt. 4. The method of claim 1, 2 or 3 which the compound or salt is administered in a pharmaceutically acceptable carrier therefor. 5. The method of claim 1, 2, 3 or 4 in which the compound or salt is administered orally. 6. The method of claim 5 in which the compound or salt is administered in a pharmaceutically acceptable carrier therefor. 7. A method of treating minimal brain dysfunction in a human suffering from same, which comprises orally administering to said human an effective non-toxic minimal brain dysfunction treatment amount of a pharmaceutically acceptable acid addition salt of the compound of formula (I) ##STR4## 8. The method of claim 7 in which the salt is the hydrochloride salt. 9. The method of claim 7 or claim 8 in which the salt is administered in a pharmaceutically acceptable carrier therefor in the form of a tablet or capsule. 10. A method of treating minimal brain dysfunction in a human suffering from same, which comprises parenterally administering to said human a parenteral composition containing an effective non-toxic minimal brain dysfunction treatment amount of a pharmaceutically acceptable acid addition salt of the compound of formula I ##STR5##

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