CLINICAL TRIALS PROFILE FOR PEVONEDISTAT
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Clinical Trials for Pevonedistat
Trial ID | Title | Status | Sponsor | Phase | Summary |
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NCT01814826 ↗ | Study of MLN4924 Plus Azacitidine in Treatment-naive Participants With Acute Myelogenous Leukemia (AML) Who Are 60 Years or Older | Completed | Millennium Pharmaceuticals, Inc. | Phase 1 | The purpose of this study is to establish the maximum tolerated dose (MTD), and to assess the safety and tolerability of MLN4924 (pevonedistat) in combination with azacitidine in treatment naive participants with AML who were 60 years of age or older. |
NCT01862328 ↗ | Dose Escalation, Multi-arm Study of MLN4924 Plus Docetaxel, Gemcitabine, or Combination of Carboplatin and Paclitaxel in Participants With Solid Tumors | Completed | Millennium Pharmaceuticals, Inc. | Phase 1 | The purpose of this study is to establish the maximum tolerated dose (MTD) and assess the safety and tolerability of MLN4924 (pevonedistat) in combination with docetaxel, paclitaxel and carboplatin, and gemcitabine in participants with solid tumors. |
NCT02610777 ↗ | An Efficacy and Safety Study of Pevonedistat Plus Azacitidine Versus Single-Agent Azacitidine in Participants With Higher-Risk Myelodysplastic Syndromes (HR MDS), Chronic Myelomonocytic Leukemia (CMML) and Low-Blast Acute Myelogenous Leukemia (AML) | Completed | Millennium Pharmaceuticals, Inc. | Phase 2 | The purpose of this study is to evaluate the efficacy and safety of pevonedistat plus azacitidine versus single-agent azacitidine in participants with HR-MDS or CMML, or low-blast AML. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Summary |
Clinical Trial Conditions for Pevonedistat
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Clinical Trial Locations for Pevonedistat
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Clinical Trial Progress for Pevonedistat
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Clinical Trial Sponsors for Pevonedistat
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