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Last Updated: May 20, 2024

CLINICAL TRIALS PROFILE FOR ENTINOSTAT

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Clinical Trials for Entinostat

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Trial ID	Title	Status	Sponsor	Phase	Summary
NCT00015925 ↗	MS-275 in Treating Patients With Hematologic Cancer	Completed	National Cancer Institute (NCI)	Phase 1	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of MS-275 in treating patients who have hematologic cancer.
NCT00015925 ↗	MS-275 in Treating Patients With Hematologic Cancer	Completed	Sidney Kimmel Comprehensive Cancer Center	Phase 1	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of MS-275 in treating patients who have hematologic cancer.
NCT00015925 ↗	MS-275 in Treating Patients With Hematologic Cancer	Completed	Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins	Phase 1	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of MS-275 in treating patients who have hematologic cancer.
NCT00020579 ↗	MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma	Completed	National Cancer Institute (NCI)	Phase 1	RATIONALE: MS-275 may stop the growth of cancer cells by blocking the enzymes necessary for their growth. PURPOSE: This phase I trial is studying the side effects and best dose of MS-275 in treating patients with advanced solid tumors or lymphoma.
NCT00020579 ↗	MS-275 in Treating Patients With Advanced Solid Tumors or Lymphoma	Completed	National Institutes of Health Clinical Center (CC)	Phase 1	RATIONALE: MS-275 may stop the growth of cancer cells by blocking the enzymes necessary for their growth. PURPOSE: This phase I trial is studying the side effects and best dose of MS-275 in treating patients with advanced solid tumors or lymphoma.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Summary

Clinical Trial Conditions for Entinostat

Condition Name

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Condition Name for
Intervention	Trials
Breast Cancer	10
Recurrent Adult Acute Myeloid Leukemia	5
Untreated Adult Acute Myeloid Leukemia	4
Secondary Acute Myeloid Leukemia	4
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Condition MeSH

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Condition MeSH for
Intervention	Trials
Breast Neoplasms	20
Carcinoma	13
Carcinoma, Non-Small-Cell Lung	11
Lung Neoplasms	11
[disabled in preview]	0
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Clinical Trial Locations for Entinostat

Trials by Country

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Trials by Country for
Location	Trials
United States	331
Japan	15
China	5
Georgia	3
Australia	3
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Trials by US State

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Trials by US State for
Location	Trials
Maryland	32
California	18
New York	16
Texas	15
Pennsylvania	15
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Clinical Trial Progress for Entinostat

Clinical Trial Phase

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Clinical Trial Phase for
Clinical Trial Phase	Trials
Phase 3	2
Phase 2	24
Phase 1/Phase 2	15
[disabled in preview]	29
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Clinical Trial Status

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Clinical Trial Status for
Clinical Trial Phase	Trials
Completed	26
Active, not recruiting	13
Recruiting	9
[disabled in preview]	14
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Clinical Trial Sponsors for Entinostat

Sponsor Name

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Sponsor Name for
Sponsor	Trials
National Cancer Institute (NCI)	30
Syndax Pharmaceuticals	27
Merck Sharp & Dohme Corp.	4
[disabled in preview]	6
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Sponsor Type

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Sponsor Type for
Sponsor	Trials
Industry	52
Other	37
NIH	31
[disabled in preview]	0
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