CLINICAL TRIALS PROFILE FOR XERAVA
✉ Email this page to a colleague
All Clinical Trials for XERAVA
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT05537896 ↗ | Prospective Evaluation of Xerava Prophylaxis in Hematological Malignancy Patients With Prolonged Neutropenia | Not yet recruiting | West Virginia University | Phase 2 | 2022-10-01 | Antibacterial prophylaxis is recommended in patients at high risk of infection, specifically patients undergoing acute leukemia induction therapy or hematopoietic stem cell transplant (HSCT) who are expected to have profound neutropenia (ANC<100 neutrophils/milliliter) for more than seven days. Xerava™ (eravacycline) has a broad spectrum of activity including many multi-drug resistant strains of bacteria. It is not an agent used for treatment of febrile neutropenia, making eravacycline a very attractive alternative to consider in this prophylactic setting. Eravacycline has activity against MRSA, VRE, and Clostridioides difficile, all of which are common problems in this patient population. It also covers the majority of enteric gram-negative pathogens while also producing satisfactory tissue penetration and adequate plasma concentrations, which has classically been a concern with prior agents. Eravacycline has activity against coagulase-negative staphylococcus, which is a common catheter-related infection in leukemia and HSCT patients. The primary objective will be report the incidence of antibiotic prophylaxis failure with eravacycline prophylaxis for hematologic malignancy patients with prolonged neutropenia. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for XERAVA
Condition Name
Clinical Trial Locations for XERAVA
Trials by Country
Clinical Trial Progress for XERAVA
Clinical Trial Phase
Clinical Trial Sponsors for XERAVA
Sponsor Name
