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Last Updated: May 19, 2024

CLINICAL TRIALS PROFILE FOR PIMOZIDE


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All Clinical Trials for PIMOZIDE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004652 ↗ Phase II Pilot Controlled Study of Short Vs Longer Term Pimozide (Orap) Therapy in Tourette Syndrome Completed University of Rochester Phase 2 1993-02-01 OBJECTIVES: I. Determine whether the time period between randomization and endpoint is longer in the short term pimozide therapy or longer term therapy in patients with Tourette syndrome. II. Determine whether tic severity, medication side effects, academic performance and psychosocial functioning are better in the short term pimozide therapy or longer term pimozide therapy.
NCT00004652 ↗ Phase II Pilot Controlled Study of Short Vs Longer Term Pimozide (Orap) Therapy in Tourette Syndrome Completed National Center for Research Resources (NCRR) Phase 2 1993-02-01 OBJECTIVES: I. Determine whether the time period between randomization and endpoint is longer in the short term pimozide therapy or longer term therapy in patients with Tourette syndrome. II. Determine whether tic severity, medication side effects, academic performance and psychosocial functioning are better in the short term pimozide therapy or longer term pimozide therapy.
NCT00158223 ↗ Effectiveness of Pimozide in Augmenting the Effects of Clozapine in the Treatment of Schizophrenia Completed National Institute of Mental Health (NIMH) Phase 4 2004-10-01 This study will assess the effectiveness of pimozide in enhancing the effects of clozapine in the treatment of schizophrenia.
NCT00158223 ↗ Effectiveness of Pimozide in Augmenting the Effects of Clozapine in the Treatment of Schizophrenia Completed Icahn School of Medicine at Mount Sinai Phase 4 2004-10-01 This study will assess the effectiveness of pimozide in enhancing the effects of clozapine in the treatment of schizophrenia.
NCT00289861 ↗ Risperidone Augmentation in Patients With Schizophrenia Completed Stanley Medical Research Institute Phase 4 2003-02-01 We propose a double-blind, placebo-controlled trial to study the effectiveness and tolerability of adding risperidone to stable yet only partially remitted patients with schizophrenia maintained on clozapine.
NCT00289861 ↗ Risperidone Augmentation in Patients With Schizophrenia Completed Massachusetts General Hospital Phase 4 2003-02-01 We propose a double-blind, placebo-controlled trial to study the effectiveness and tolerability of adding risperidone to stable yet only partially remitted patients with schizophrenia maintained on clozapine.
NCT00374244 ↗ Efficacy of Pimozide Augmentation for Clozapine Partial Response Completed Stanley Medical Research Institute Phase 2 2004-01-01 This is a 12 week outpatient study for patients with schizophrenia who are on Clozapine, but continue to experience symptoms. The purpose of this project is to find out if small doses of pimozide (an antipsychotic medication, taken by mouth) will be helpful in reducing symptoms (such as hearing voices, having trouble in organizing your thoughts, lack of interest in life events and social activities), compared to placebo (an inactive substance, "sugar pill"), when added to clozapine in patients with schizophrenia. The participant will be asked to come in once a week to meet with the research staff and study doctor. The participant will continue to see your regular clinician during this study for all normal appointments. The participant will remain on your current medications throughout the study. During the study you will be randomly selected to be put on a small dose of Pimozide or placebo.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for PIMOZIDE

Condition Name

Condition Name for PIMOZIDE
Intervention Trials
Schizophrenia 7
Stress Disorders, Post-Traumatic 2
Psychotic Disorders 2
Drug-induced QT Prolongation 1
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Condition MeSH

Condition MeSH for PIMOZIDE
Intervention Trials
Schizophrenia 7
Psychotic Disorders 4
Mental Disorders 3
Disease 3
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Clinical Trial Locations for PIMOZIDE

Trials by Country

Trials by Country for PIMOZIDE
Location Trials
United States 35
Spain 9
Canada 7
United Kingdom 2
Germany 2
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Trials by US State

Trials by US State for PIMOZIDE
Location Trials
New York 5
California 3
North Carolina 2
New Mexico 2
Connecticut 2
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Clinical Trial Progress for PIMOZIDE

Clinical Trial Phase

Clinical Trial Phase for PIMOZIDE
Clinical Trial Phase Trials
Phase 4 3
Phase 3 2
Phase 2 7
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Clinical Trial Status

Clinical Trial Status for PIMOZIDE
Clinical Trial Phase Trials
Completed 12
Not yet recruiting 3
Withdrawn 2
[disabled in preview] 4
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Clinical Trial Sponsors for PIMOZIDE

Sponsor Name

Sponsor Name for PIMOZIDE
Sponsor Trials
VA Office of Research and Development 2
University of Calgary 2
Stanley Medical Research Institute 2
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Sponsor Type

Sponsor Type for PIMOZIDE
Sponsor Trials
Other 30
U.S. Fed 6
Industry 2
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