Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure
Terminated
H. Lundbeck A/S
N/A
2009-01-01
The primary objective is to evaluate the Patent Ductus Arteriosus (PDA) closure rate of early
vs. late use of Ibuprofen (Ibu). The investigators believe that early use of Ibu will have a
higher PDA closure rate than later use of Ibu. Early use is defined as medication given
before the infant reaches 96 hrs old. Late use is defined as medication given when infant is
more than 96 hrs old.
Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure
Terminated
University of Utah
N/A
2009-01-01
The primary objective is to evaluate the Patent Ductus Arteriosus (PDA) closure rate of early
vs. late use of Ibuprofen (Ibu). The investigators believe that early use of Ibu will have a
higher PDA closure rate than later use of Ibu. Early use is defined as medication given
before the infant reaches 96 hrs old. Late use is defined as medication given when infant is
more than 96 hrs old.
Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates
Terminated
OSF Healthcare System
Phase 4
2009-08-01
The purpose of this study is to determine if increasing the ibuprofen dose will increase the
likelihood of closing the patent ductus arteriosus in premature babies.
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