Duration of Sciatic Nerve Block After Injection of Local Anesthetic In or Around the Nerve
Completed
University of Parma
Phase 4
2012-10-01
This study was designed to assess whether the injection of local anesthetic into the nerve
(intraneural), as opposed to around it (perineural), leads to longer anesthesia and analgesia
of the leg.
Some reports of accidental intraneural injection mention an extremely long duration. When
different drugs and doses were evaluated in a clinical trial of intraneural injection, a
longer-than-expected duration was reported.
The investigators will compare the two types of injection using the same drug, so as to
determine if there is an actual difference in duration.
Spinal Anesthesia Versus Combined Sciatic-femoral Nerve Block for Outpatient Knee Arthroscopy
Completed
ASST Gaetano Pini-CTO
Phase 4
2015-01-01
The aim of the study is to compare the time of home discharge in day-case patients receiving
either a spinal anesthesia or a combined sciatic-femoral nerve block for knee arthroscopy
The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability
Completed
Innovation Fund Denmark
Phase 4
2016-07-01
The aim is to investigate the effect of perineural administration of a series of different
volumes of local anaesthesia (ropivacaine 0.2%) on nerve block duration and the variability
of the duration in the common peroneal nerve and the sciatic nerve in healthy volunteers.
The hypothesis is that nerve block duration is correlated to local anaesthetic volume, but
only to a certain degree. After a sufficient volume a 'saturation level' will be reached, and
nerve block duration will not increase further.
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