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Profile for Tradename: CYCLOSET

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Cycloset is a drug marketed by Veroscience and is included in one NDA. It is available from one supplier. There are eight patents protecting this drug.

This drug has one hundred and eighteen patent family members in twenty-eight countries.

The generic ingredient in CYCLOSET is bromocriptine mesylate. There are nine drug master file entries for this compound. Two suppliers are listed for this compound. Additional details are available on the bromocriptine mesylate profile page.

Summary for Tradename: CYCLOSET

Patents:8
Applicants:1
NDAs:1
Suppliers / Packagers: see list3

Pharmacology for Tradename: CYCLOSET

Ingredient-typeErgolines
Drug ClassErgot Derivative

Clinical Trials for: CYCLOSET

Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Exclusivity Expiration
Veroscience
CYCLOSET
bromocriptine mesylate
TABLET;ORAL020866-001May 5, 2009RXYes5,716,957<disabled><disabled>
Veroscience
CYCLOSET
bromocriptine mesylate
TABLET;ORAL020866-001May 5, 2009RXYes8,137,994<disabled><disabled>
Veroscience
CYCLOSET
bromocriptine mesylate
TABLET;ORAL020866-001May 5, 2009RXYes8,431,155<disabled>Y<disabled>
Veroscience
CYCLOSET
bromocriptine mesylate
TABLET;ORAL020866-001May 5, 2009RXYes5,679,685<disabled>Y<disabled>
Veroscience
CYCLOSET
bromocriptine mesylate
TABLET;ORAL020866-001May 5, 2009RXYes8,613,947<disabled>Y<disabled>
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Non-Orange Book Patents for Tradename: CYCLOSET

For Orange Book-listed patents (shown in the main table above) generic applications must certify that the listed patents are expired, invalid, or will not be infringed by generic entry.

The non-Orange Book patents listed below do not require formal certifications, so they do not automatically impede generic entry. Instead, they represent potential opportunities for branded firms to block generic entry through patent infringment challenges.

Patent No. Title Estimated Patent Expiration
5,872,127 Method of regulating immune function<disabled in preview>
5,905,083 Method of treating rheumatoid arthritis<disabled in preview>
5,716,962 Process for therapeutically modifying and resetting prolactin rhythm with a dopamine agonist<disabled in preview>
5,635,512 Method for modifying or resetting the prolactin rhythm of an insulin insensitive or diabetic animal or human<disabled in preview>
5,756,513 Therapeutic process for the treatment of the pathologies of type II diabetes<disabled in preview>
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International Patent Family for Tradename: CYCLOSET

Country Document Number Publication Date
Israel114300Oct 31, 1995
Germany69133595May 21, 2008
Canada2179540Jun 29, 1995
World Intellectual Property Organization (WIPO)9312793Jul 08, 1993
Russian Federation2104698Feb 20, 1998
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Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.

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ISSN: 2162-2639

Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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