Details for Patent: 5,834,010
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Summary for Patent: 5,834,010
Title: | Triacetin as a penetration enhancer for transdermal delivery of a basic drug |
Abstract: | A composition and method for enhancing transdermal penetration of a basic drug are described. The composition comprises a matrix patch comprising an effective amount of a basic drug, preferably having a pK.sub.a of about 8.0 or greater, an effective amount of a penetration enhancer consisting essentially of triacetin, and a polymer layer preferably comprising a pressure-sensitive adhesive. A preferred basic drug is oxybutynin and acid addition salts thereof. The method for enhancing transdermal penetration comprises applying the matrix patch to a selected area of skin. |
Inventor(s): | Quan; Danyi (Salt Lake City, UT), Deshpanday; Ninad A. (Salt Lake City, UT), Venkateshwaran; Srinivasan (Salt Lake City, UT), Ebert; Charles D. (Salt Lake City, UT) |
Assignee: | Theratech, Inc. (Salt Lake City, UT) |
Application Number: | 08/775,367 |
Patent Claim Types: see list of patent claims | Use; Composition; |
Drugs Protected by US Patent 5,834,010
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International Family Members for US Patent 5,834,010
Country | Patent Number | Estimated Expiration | Supplementary Protection Certificate | SPC Country | SPC Expiration |
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Argentina | 001721 | ⤷ Try a Trial | |||
Austria | 205694 | ⤷ Try a Trial | |||
Australia | 5446796 | ⤷ Try a Trial | |||
Australia | 696777 | ⤷ Try a Trial | |||
>Country | >Patent Number | >Estimated Expiration | >Supplementary Protection Certificate | >SPC Country | >SPC Expiration |