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Patent: 5,643,607

Summary for Patent: 5,643,607

Title: Prolonged release microcapsules
Abstract:This invention provides a microcapsule designed for zero order release of a physiologically active polypeptide over a period of at least two months, which is produced by preparing a water-in-oil emulsion comprising an inner aqueous layer containing about 20 to 70% (w/w) of said polypeptide and an oil layer containing a copolymer or homopolymer having a weight-average molecular weight of 7,000 to 30,000, wherein the composition ratio of lactic acid/glycolic acid in the copolymer or homopolymer is 80/10 to 100/0, and then subjecting said water-in oil emulsion to microencapsulation.
Inventor(s): Okada; Hiroaki (Suita, JP), Inoue; Yayoi (Kyoto, JP), Ogawa; Yasuaki (Otokuni-gun, JP)
Assignee: Takeda Chemical Industries, Ltd. (Osaka, JP)
Application Number:08/458,679
Patent Claim Types:
see list of patent claims
Compound; Dosage form; Process;
Patent PDF download available with subscription

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Foreign Priority and PCT Information for Patent: 5,643,607

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan2-033133Feb 13, 1990

International Patent Family for Patent: 5,643,607

Country Document Number Publication Date
Austria123413Jun 15, 1995
Australia8179491Aug 06, 1992
Australia645108Jan 06, 1994
Brazil9103553Sep 29, 1992
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