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Patent: 5,637,611

Summary for Patent: 5,637,611

Title: Medicaments
Abstract:Use of a compound of general formula (I): ##STR1## wherein: R.sup.1 represents hydrogen, halogen, trifluoromethyl, nitro, hydroxy, C.sub.1-6 alkyl, C.sub.1-6 alkoxy, arylC.sub.1-6 alkoxy, --CO.sub.2 R.sup.4, --(CH.sub.2).sub.n CN, --(CH.sub.2).sub.n CONR.sup.5 R.sup.6, --(CH.sub.2).sub.n SO.sub.2 NR.sup.5 R.sup.6, C.sub.1-6 alkanoylamino (CH.sub.2).sub.n, or C.sub.1-6 alkylsulphonylamino (CH.sub.2).sub.n ; R.sup.4 represents hydrogen, C.sub.1-6 alkyl or arylC.sub.1-6 alkyl; R.sup.5 and R.sup.6 each independently represent hydrogen or C.sub.1-6 alkyl, or R.sup.5 and R.sup.6 together with the nitrogen atom to which they are attached form a ring; n represents 0, 1 or 2; and R.sup.2 and R.sup.3 each independently represent hydrogen, C.sub.1-6 alkyl or benzyl or together with the nitrogen atom to which they are attached form a pyrrolidino, piperidino or hexahydroazepino ring; or a physiologically acceptable salt thereof, in the manufacture of a medicament for the treatment of a condition where a 5-HT.sub.1 -like agonist is indicated, for example migraine. Novel compounds of formula (I), processes for preparing them and pharmaceutical compositions containing them are also described.
Inventor(s): King; Francis D. (Harlow, GB2), Gaster; Laramie M. (Harlow, GB2), Kaumann; Alberto J. (Trumpington, GB2), Young; Rodney C. (Hertford, GB2)
Assignee: SmithKline Beecham p.l.c. (GB2)
Application Number:08/442,719
Patent Claim Types:
see list of patent claims
Compound; Composition; Use;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Endo Pharms
FROVA
frovatriptan succinate
TABLET;ORAL021006Nov 8, 2001RXYes5,637,611<disabled>ACUTE TREATMENT OF MIGRAINE ATTACKS WITH OR WITHOUT AURA IN ADULTS
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Patent activity for: 5,637,611

Disclaimer
Filing: 5,637,611 - Francis D. King; Laramie M. Gaster, both of Harlow; Alberto J. Kaumann, Trumpington; Rodney C. Young, Hertford, all of England. MEDICAMENTS.
Patent dated June 10, 1997. Disclaimer filed October 30, 2013, by the assignee, Endo Pharmaceuticals Inc.
Disclaimer
Filing:Pat. No. 5,637,611 and 5,464,864.

International Patent Family for Patent: 5,637,611

Country Document Number Publication Date
South Africa9204658Dec 24, 1993
WIPO (PCT)9300086Jan 07, 1993
United States5464864Nov 07, 1995
United States5827871Oct 27, 1998
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