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Patent: 5,563,138

Summary for Patent: 5,563,138

Title: Benzoheterocyclic compounds
Abstract:Novel 4-oxoquinoline-3-carboxylic acid compounds of the formula: ##STR1## wherein R.sup.1 is cyclopropyl which may have 1 to 3 substituents of alkyl and halogen; phenyl which may be substituted by 1 to 3 substituents of alkoxy, halogen and OH; alkyl which may be substituted by halogen, alkanoyloxy or OH; alkenyl; or thienyl, R.sup.2 is 5- to 9-membered saturated or unsaturated heterocyclic ring which may be sustituted, R.sup.3 is alkyl, R is H or alkyl, and X is halogen, and pharmaceutically acceptable salts thereof, said compounds having excellent antimicrobial activity and hence being useful as an antimicrobial agent, and a pharmaceutical composition containing said compound as an active ingredient.
Inventor(s): Ueda; Hiraki (Mishima, JP), Miyamoto; Hisashi (Tokushima, JP), Yamashita; Hiroshi (Tokushima, JP), Tone; Hitoshi (Itano, JP)
Assignee: Otsuka Pharmaceutical Company, Limited (Tokyo, JP)
Application Number:07/179,239
Patent Claim Types:
see list of patent claims
Compound; Composition;
Patent PDF download available with subscription

Glossary
Applicant Tradename Generic Name Dosage NDA Approval Date Type RLD Patent No. Patent Expiration Product Substance Delist Req. Patented / Exclusive Use
Otsuka
RAXAR
grepafloxacin hydrochloride
TABLET;ORAL020695Nov 6, 1997DISCNNo5,563,138<disabled>
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Foreign Priority and PCT Information for Patent: 5,563,138

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
Japan62-94198Apr 16, 1987
Japan62-102351Apr 24, 1987
Japan62-108361Apr 30, 1987
Japan62-126598May 22, 1987

International Patent Family for Patent: 5,563,138

Country Document Number Publication Date
China1030237Jan 11, 1989
China1053666Jun 21, 2000
Cyprus2050Apr 30, 1998
Germany19775083Jun 13, 2001
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