
| Title: | Pregna-1,4-diene3,20-dione-16-17-acetal-21 esters, process for their preparation, composition, and methods for the treatment of inflammatory conditions |
| Abstract: | The present invention relates to compounds of the formula: ##STR1## in which X.sub.1 and X.sub.2 correspond to H or F without distinction; R.sub.1 represents the following radicals: ##STR2## and R.sub.2 represents the radicals ##STR3## in the form of an R epimer, an S epimer, or a stereoisomeric mixture of the R and S epimers in terms of the orientation of the substituents on the carbon atom at position 22, novel intermediates and a method of their preparation by hydrolysis-ketalization, and use of such compounds as drugs and/or therapeutic agents. |
| Inventor(s): | Calatayud; Jose (Madrid, ES), Conde; Jose R. (Madrid, ES), Luna; Manuel (Madrid, ES) |
| Assignee: | Especialidades Latinas Medicamentos Universales, S.A. (Elmu, S.A.) (Madrid, ES) |
| Application Number: | 08/278,112 |
| Patent Claim Types: | Compound; Use; Composition; Dosage form; |
| Applicant | Tradename | Generic Name | NDA | Approval Date | Type | RLD | Patent Number | Product | Substance | Delist Req. | Patent Expiration | Patented / Exclusive Use |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Nycomed Us | ALVESCO | ciclesonide | 021658 | Jan 10, 2008 | RX | No | 5,482,934 | Y | Y | Oct 24, 2017 | METHOD OF TREATING INFLAMMATORY CONDITIONS | |
| Nycomed Us | ALVESCO | ciclesonide | 021658 | Jan 10, 2008 | RX | Yes | 5,482,934 | Y | Y | Oct 24, 2017 | METHOD OF TREATING INFLAMMATORY CONDITIONS | |
| Nycomed Us | OMNARIS | ciclesonide | 022004 | Oct 20, 2006 | RX | Yes | 5,482,934 | Y | Y | Oct 24, 2017 | NASAL TREATMENT OF SEASONAL AND PERENNIAL ALLERGIC RHINITIS SYMPTOMS |
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