Details for Patent: 5,424,078
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Summary for Patent: 5,424,078
Title: | Aqueous ophthalmic formulations and methods for preserving same |
Abstract: | Stabilized chlorine dioxide is a preservative for ophthalmic formulations. The stabilized chlorine dioxide, when employed as a preservative ophthalmic formulations is preferably present in an amount of from about 0.0002 or about 0.002 to about 0.02 weight/volume percent. The aqueous ophthalmic formulations, in addition to the stabilized chlorine dioxide and the water which functions as a vehicle for the formulations, contains an ophthalmically acceptable tonicity component effective to maintain the osmolality of the formulation at least about 200 mOsmol/kg, and a buffer to maintain the pH of the ophthalmic formulation within an acceptable physiological range. A method for preserving aqueous ophthalmic formulations utilizing stabilized chlorine dioxide is also set forth. |
Inventor(s): | Dziabo; Anthony J. (El Toro, CA), Ripley; Paul S. (Irvine, CA) |
Assignee: | Allergan, Inc. (Irvine, CA) |
Application Number: | 07/694,640 |
Patent Claim Types: see list of patent claims | Use; Formulation; |
Drugs Protected by US Patent 5,424,078
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International Family Members for US Patent 5,424,078
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