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Details for Patent: 7,214,692

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Summary for Patent: 7,214,692

Title:Medical use for tachykinin antagonists
Abstract:The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel tachykinin antagonists of formula (I), processes for their preparation, pharmaceutical compositions containing them and their medical use. ##STR00001## wherein R represents the ring A ##STR00002## or 2-pyridinyl or 2-pyridinyl-N-oxide; R.sup.1 is selected from halogen atoms and C.sub.1-4alkyl, C.sub.1-4alkoxy, trifluoromethyl, and S(O).sub.nC.sub.1-4alkyl groups; R.sup.2 and R.sup.3, which may be the same or different, each independently are selected from hydrogen and halogen atoms and C.sub.1-4alkyl, C.sub.1-4alkoxy, trifluoromethyl and cyano groups; n represents zero, 1 or 2; and pharmaceutically acceptable salts and solvates thereof.
Inventor(s): Hagan; Russell Michael (Ware, GB), Bunce; Keith Thomas (Ware, GB)
Assignee: Glaxo Group Limited (Middlesex, GB)
Application Number:09/985,679
Patent Claim Types:
see list of patent claims
Use; Composition;
Patent PDF download available with subscription

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Foreign Priority and PCT Information for Patent: 7,214,692

Foriegn Application Priority Data
Foreign Country Foreign Patent Number Foreign Patent Date
United Kingdom9120172.3Sep 20, 1991
United Kingdom9202839.8Feb 11, 1992
United Kingdom9204151.5Feb 27, 1992

International Patent Family for Patent: 7,214,692

Country Document Number Publication Date
European Patent Office1082959Mar 14, 2001
Japan3020757Mar 15, 2000
European Patent Office0916346May 19, 1999
Portugal533280Jan 31, 2001
European Patent Office0533280Mar 24, 1993
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Preferred citation:

Friedman, Y. Location of pharmaceutical innovation: 2000–2009 Nature Reviews Drug Discovery 9, 835–836 (2010).

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