Patent 7,214,692 protects and is included in zero NDA.
|Title:||Medical use for tachykinin antagonists|
|Abstract:||The present invention relates to the use of tachykinin antagonists, including substance P antagonists and other neurokinin antagonists, in the treatment of emesis. Also described are novel tachykinin antagonists of formula (I), processes for their preparation, pharmaceutical compositions containing them and their medical use. ##STR00001## wherein R represents the ring A ##STR00002## or 2-pyridinyl or 2-pyridinyl-N-oxide; R.sup.1 is selected from halogen atoms and C.sub.1-4alkyl, C.sub.1-4alkoxy, trifluoromethyl, and S(O).sub.nC.sub.1-4alkyl groups; R.sup.2 and R.sup.3, which may be the same or different, each independently are selected from hydrogen and halogen atoms and C.sub.1-4alkyl, C.sub.1-4alkoxy, trifluoromethyl and cyano groups; n represents zero, 1 or 2; and pharmaceutically acceptable salts and solvates thereof.|
|Inventor(s):||Hagan; Russell Michael (Ware, GB), Bunce; Keith Thomas (Ware, GB)|
|Assignee:||Glaxo Group Limited (Middlesex, GB)|
Patent Claim Types:|
see list of patent claims
|Country||Document Number||Publication Date|
|South Africa||9207156||Mar 18, 1994|
|United States of America||2002052351||May 02, 2002|
|United States of America||5360820||Nov 01, 1994|
|United States of America||5538982||Jul 23, 1996|
|United States of America||5798363||Aug 25, 1998|
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